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Literature DB >> 14587774

Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection.

Thomas D Wang¹, Christopher H Contag, Michael J Mandella, Ning Y Chan, Gordon S Kino.

Abstract

We present a dual-axes confocal microscope that employs postobjective scanning and low-coherence heterodyne detection to collect vertical cross-sectional images from biological tissue with high axial resolution, reduced noise from scattered light, deep tissue penetration, and a large dynamic range. This architecture can be scaled down to millimeter dimensions with microelectromechanical systems technology for performance of in vivo optical biopsy.

Mesh：

Year: 2003 PMID： 14587774 PMCID： PMC2104522 DOI： 10.1364/ol.28.001915

Source DB: PubMed Journal: Opt Lett ISSN： 0146-9592 Impact factor: 3.776

4 in total

1. Speckle reduction in optical coherence tomography by "path length encoded" angular compounding.

Authors: N Iftimia; B E Bouma; G J Tearney
Journal: J Biomed Opt Date: 2003-04 Impact factor: 3.170

2. Dual-axis confocal microscope for high-resolution in vivo imaging.

Authors: Thomas D Wang; Michael J Mandella; Christopher H Contag; Gordon S Kino
Journal: Opt Lett Date: 2003-03-15 Impact factor: 3.776

3. Confocal theta fluorescence microscopy with annular apertures.

Authors: S Lindek; C Cremer; E H Stelzer
Journal: Appl Opt Date: 1996-01-01 Impact factor: 1.980

4. Confocal microscope with large field and working distance.

Authors: R H Webb; F Rogomentich
Journal: Appl Opt Date: 1999-08-01 Impact factor: 1.980

4 in total

12 in total

1. Confocal fluorescence microscope with dual-axis architecture and biaxial postobjective scanning.

Authors: Thomas D Wang; Christopher H Contag; Michael J Mandella; Ning Y Chan; Gordon S Kino
Journal: J Biomed Opt Date: 2004 Jul-Aug Impact factor: 3.170

Review 2. Optical biopsy: a new frontier in endoscopic detection and diagnosis.

Authors: Thomas D Wang; Jacques Van Dam
Journal: Clin Gastroenterol Hepatol Date: 2004-09 Impact factor: 11.382

Review 3. Fiber-optic fluorescence imaging.

Authors: Benjamin A Flusberg; Eric D Cocker; Wibool Piyawattanametha; Juergen C Jung; Eunice L M Cheung; Mark J Schnitzer
Journal: Nat Methods Date: 2005-12 Impact factor: 28.547

4. Dual-axes confocal reflectance microscope for distinguishing colonic neoplasia.

Authors: Jonathan T C Liu; Michael J Mandella; Shai Friedland; Roy Soetikno; James M Crawford; Christopher H Contag; Gordon S Kino; Thomas D Wang
Journal: J Biomed Opt Date: 2006 Sep-Oct Impact factor: 3.170

5. Improved rejection of multiply scattered photons in confocal microscopy using dual-axes architecture.

Authors: Larry K Wong; Michael J Mandella; Gordon S Kino; Thomas D Wang
Journal: Opt Lett Date: 2007-06-15 Impact factor: 3.776

6. Optimizing the performance of dual-axis confocal microscopes via Monte-Carlo scattering simulations and diffraction theory.

Authors: Ye Chen; Jonathan T C Liu
Journal: J Biomed Opt Date: 2013-06 Impact factor: 3.170