PURPOSE: To compare the apparent diffusion coefficients (ADCs) of myxoid and nonmyxoid soft-tissue tumors using line-scan diffusion-weighted imaging (LSDWI), and to investigate the myxoid matrix influence on ADCs of soft-tissue tumors. MATERIALS AND METHODS: This study enrolled 44 patients with soft tissue tumors. They were divided into two groups: one with myxoid-containing soft-tissue tumors (N = 23) and the other with nonmyxoid soft-tissue tumors (N = 21). The 44 patients were also classified histologically into 26 with malignant soft-tissue tumors and 18 with benign soft-tissue tumors. LSDWI was performed using b values of 5 and 1000 second/mm(2). The ADCs of the tumors were calculated and compared for myxoid and nonmyxoid tumors and for benign and malignant tumors. RESULTS: The ADC (mean +/- SD) was 1.92 +/- 0.41 x 10(-3) mm(2)/second in myxoid containing tumors, whereas the ADC was 0.97 +/- 0.33 x 10(-3) mm(2)/second in nonmyxoid tumors. The ADCs of the myxoid and nonmyxoid tumors were significantly different (P < 0.01). The ADCs were 1.45 +/- 0.59 x 10(-3) mm(2)/second in malignant tumors and 1.50 +/- 0.64 x 10(-3) mm(2)/second in benign tumors. The ADCs of benign and malignant soft-tissue tumors were not significantly different. CONCLUSION: The ADCs of myxoid-containing soft-tissue tumors were significantly higher than those of nonmyxoid soft-tissue tumors. The myxoid matrix influences ADCs of both benign and malignant soft-tissue tumors. (c) 2007 Wiley-Liss, Inc.
PURPOSE: To compare the apparent diffusion coefficients (ADCs) of myxoid and nonmyxoid soft-tissue tumors using line-scan diffusion-weighted imaging (LSDWI), and to investigate the myxoid matrix influence on ADCs of soft-tissue tumors. MATERIALS AND METHODS: This study enrolled 44 patients with soft tissue tumors. They were divided into two groups: one with myxoid-containing soft-tissue tumors (N = 23) and the other with nonmyxoid soft-tissue tumors (N = 21). The 44 patients were also classified histologically into 26 with malignant soft-tissue tumors and 18 with benign soft-tissue tumors. LSDWI was performed using b values of 5 and 1000 second/mm(2). The ADCs of the tumors were calculated and compared for myxoid and nonmyxoid tumors and for benign and malignant tumors. RESULTS: The ADC (mean +/- SD) was 1.92 +/- 0.41 x 10(-3) mm(2)/second in myxoid containing tumors, whereas the ADC was 0.97 +/- 0.33 x 10(-3) mm(2)/second in nonmyxoid tumors. The ADCs of the myxoid and nonmyxoid tumors were significantly different (P < 0.01). The ADCs were 1.45 +/- 0.59 x 10(-3) mm(2)/second in malignant tumors and 1.50 +/- 0.64 x 10(-3) mm(2)/second in benign tumors. The ADCs of benign and malignant soft-tissue tumors were not significantly different. CONCLUSION: The ADCs of myxoid-containing soft-tissue tumors were significantly higher than those of nonmyxoid soft-tissue tumors. The myxoid matrix influences ADCs of both benign and malignant soft-tissue tumors. (c) 2007 Wiley-Liss, Inc.
Authors: Nicholas Bhojwani; Peter Szpakowski; Sasan Partovi; Martin H Maurer; Ulrich Grosse; Hendrik von Tengg-Kobligk; Lisa Zipp-Partovi; Nathan Fergus; Christos Kosmas; Konstantin Nikolaou; Mark R Robbin Journal: Quant Imaging Med Surg Date: 2015-10
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