Literature DB >> 17497616

Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.

Samu Melkko1, Yixin Zhang, Christoph E Dumelin, Jörg Scheuermann, Dario Neri.   

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Year:  2007        PMID： 17497616     DOI： 10.1002/anie.200700654

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  21 in total

1.  High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries.

Authors:  Luca Mannocci; Yixin Zhang; Jörg Scheuermann; Markus Leimbacher; Gianluca De Bellis; Ermanno Rizzi; Christoph Dumelin; Samu Melkko; Dario Neri
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-10       Impact factor: 11.205

Review 2.  DNA-encoded chemistry: enabling the deeper sampling of chemical space.

Authors:  Robert A Goodnow; Christoph E Dumelin; Anthony D Keefe
Journal:  Nat Rev Drug Discov       Date:  2016-12-09       Impact factor: 84.694

3.  Bile Acid Conjugated DNA Chimera that Conditionally Inhibits Carbonic Anhydrase-II in the Presence of MicroRNA-21.

Authors:  Xiaozhu Chu; Cooper H Battle; Nan Zhang; Gyan H Aryal; Madhusoodanan Mottamal; Janarthanan Jayawickramarajah
Journal:  Bioconjug Chem       Date:  2015-07-31       Impact factor: 4.774

Review 4.  DNA as a versatile chemical component for catalysis, encoding, and stereocontrol.

Authors:  Scott K Silverman
Journal:  Angew Chem Int Ed Engl       Date:  2010-09-24       Impact factor: 15.336

5.  Translation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection.

Authors:  Brian N Tse; Thomas M Snyder; Yinghua Shen; David R Liu
Journal:  J Am Chem Soc       Date:  2008-10-29       Impact factor: 15.419

6.  Selection of bead-displayed, PNA-encoded chemicals.

Authors:  Natalie R Gassman; J Patrick Nelli; Samrat Dutta; Adam Kuhn; Keith Bonin; Zbigniew Pianowski; Nicolas Winssinger; Martin Guthold; Jed C Macosko
Journal:  J Mol Recognit       Date:  2010 Sep-Oct       Impact factor: 2.137

7.  In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors.

Authors:  Ralph E Kleiner; Christoph E Dumelin; Gerald C Tiu; Kaori Sakurai; David R Liu
Journal:  J Am Chem Soc       Date:  2010-08-25       Impact factor: 15.419

8.  Droplet microfluidic technology for single-cell high-throughput screening.

Authors:  Eric Brouzes; Martina Medkova; Neal Savenelli; Dave Marran; Mariusz Twardowski; J Brian Hutchison; Jonathan M Rothberg; Darren R Link; Norbert Perrimon; Michael L Samuels
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-15       Impact factor: 11.205

9.  Oligonucleotide-Based Systems for Input-Controlled and Non-Covalently Regulated Protein-Binding.

Authors:  Cooper Battle; Xiaozhu Chu; Janarthanan Jayawickramarajah
Journal:  Supramol Chem       Date:  2013-01-01       Impact factor: 1.688

10.  Reactivity-dependent PCR: direct, solution-phase in vitro selection for bond formation.

Authors:  David J Gorin; Adam S Kamlet; David R Liu
Journal:  J Am Chem Soc       Date:  2009-07-08       Impact factor: 15.419
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