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Literature DB >> 20669202

DNA as a versatile chemical component for catalysis, encoding, and stereocontrol.

Abstract

DNA (deoxyribonucleic acid) is the genetic material common to all of Earth's organisms. Our biological understanding of DNA is extensive and well-exploited. In recent years, chemists have begun to develop DNA for nonbiological applications in catalysis, encoding, and stereochemical control. This Review summarizes key advances in these three exciting research areas, each of which takes advantage of a different subset of DNA's useful chemical properties.

Entities: Chemical Disease Species

Mesh：

Substances：
RNA, Catalytic
DNA

Year: 2010 PMID： 20669202 PMCID： PMC3268559 DOI： 10.1002/anie.200906345

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

220 in total

1. A deoxyribozyme that forms a three-helix-junction complex with its RNA substrates and has general RNA branch-forming activity.

Authors: Rebecca L Coppins; Scott K Silverman
Journal: J Am Chem Soc Date: 2005-03-09 Impact factor: 15.419

2. Essential role of an active-site guanine in glmS ribozyme catalysis.

Authors: Daniel J Klein; Michael D Been; Adrian R Ferré-D'Amaré
Journal: J Am Chem Soc Date: 2007-11-09 Impact factor: 15.419

Review 3. Forty years of in vitro evolution.

Authors: Gerald F Joyce
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

4. Engineering a selective small-molecule substrate binding site into a deoxyribozyme.

Authors: Claudia Höbartner; Scott K Silverman
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

5. DNA computers for work and play.

Authors: Joanne Macdonald; Darko Stefanovic; Milan N Stojanovic
Journal: Sci Am Date: 2008-11 Impact factor: 2.142

6. Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.

Authors: Joonhee Han; John M Burke
Journal: Biochemistry Date: 2005-05-31 Impact factor: 3.162

7. Capping DNA with DNA.

Authors: Y Li; Y Liu; R R Breaker
Journal: Biochemistry Date: 2000-03-21 Impact factor: 3.162

8. A DNA metalloenzyme with DNA ligase activity.

Authors: B Cuenoud; J W Szostak
Journal: Nature Date: 1995-06-15 Impact factor: 49.962

9. Enantioselective Friedel-Crafts reactions in water using a DNA-based catalyst.

Authors: Arnold J Boersma; Ben L Feringa; Gerard Roelfes
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

10. DNA-catalyzed sequence-specific hydrolysis of DNA.

Authors: Madhavaiah Chandra; Amit Sachdeva; Scott K Silverman
Journal: Nat Chem Biol Date: 2009-08-16 Impact factor: 15.040

41 in total

1. Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme.

Authors: Ying Xiao; Madhavaiah Chandra; Scott K Silverman
Journal: Biochemistry Date: 2010-11-09 Impact factor: 3.162

2. DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates.

Authors: On Yi Wong; P I Pradeepkumar; Scott K Silverman
Journal: Biochemistry Date: 2011-05-03 Impact factor: 3.162

3. DNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage.

Authors: Amit Sachdeva; Scott K Silverman
Journal: Org Biomol Chem Date: 2011-11-01 Impact factor: 3.876

DNA as a versatile chemical component for catalysis, encoding, and stereocontrol.

1. A deoxyribozyme that forms a three-helix-junction complex with its RNA substrates and has general RNA branch-forming activity.

2. Essential role of an active-site guanine in glmS ribozyme catalysis.

Review 3. Forty years of in vitro evolution.

4. Engineering a selective small-molecule substrate binding site into a deoxyribozyme.

5. DNA computers for work and play.

6. Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.

7. Capping DNA with DNA.

8. A DNA metalloenzyme with DNA ligase activity.

9. Enantioselective Friedel-Crafts reactions in water using a DNA-based catalyst.

10. DNA-catalyzed sequence-specific hydrolysis of DNA.

1. Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme.

2. DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates.

3. DNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage.

Review 4. Arylation Chemistry for Bioconjugation.

5. Covalent tagging of phosphorylated peptides by phosphate-specific deoxyribozymes.

6. DNA-catalyzed glycosylation using aryl glycoside donors.

7. DNA-catalyzed hydrolysis of esters and aromatic amides.

Review 8. The RNA World: molecular cooperation at the origins of life.

9. Lanthanide ions as required cofactors for DNA catalysts.

10. Enhanced deoxyribozyme-catalyzed RNA ligation in the presence of organic cosolvents.