Literature DB >> 17476552

Is OPTAx useful for monitoring the effect of stimulants on hyperactivity and inattention? A brief report.

Janne Tabori-Kraft1, Merete Juul Sørensen, Martin Kaergaard, Søren Dalsgaard, Per Hove Thomsen.   

Abstract

PURPOSE: The purpose of this study was to investigate whether OPTAx, an objective measurement of hyperactivity, impulsivity and inattention can be used to measure the positive clinical effect of stimulants found in children with hyperkinetic disorder (HKD) or attention deficit disorder without hyperactivity.
METHOD: A total of 22 boys and one girl, with ages ranging between 7-12 years, diagnosed with HKD or attention deficit disorder without hyperactivity and receiving treatment with stimulants were tested with OPTAx, with and without stimulants. The main parameters investigated were: displacement, area, accuracy, variability, errors of commission and errors of omission.
RESULTS: OPTAx showed a significant improvement on all parameters during stimulant treatment compared with no treatment. The improvement measured by OPTAx was supported by clinical assessment, which found that 95% of the children improved much or very much on the Clinical Global Assessment Scale during stimulant treatment.
CONCLUSIONS: The objective parameters of the OPTAx reflected the clinical improvement found in children with HKD or attention deficit disorder without hyperactivity during stimulant treatment. This suggests a greater role for objective measurements such as OPTAx in daily clinical practise.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17476552     DOI: 10.1007/s00787-006-0571-2

Source DB:  PubMed          Journal:  Eur Child Adolesc Psychiatry        ISSN: 1018-8827            Impact factor:   4.785


  19 in total

1.  The treatment of attention-deficit hyperactivity disorder: an annotated bibliography and critical appraisal of published systematic reviews and metaanalyses.

Authors:  A R Jadad; L Booker; M Gauld; R Kakuma; M Boyle; C E Cunningham; M Kim; R Schachar
Journal:  Can J Psychiatry       Date:  1999-12       Impact factor: 4.356

2.  Functional deficits in basal ganglia of children with attention-deficit/hyperactivity disorder shown with functional magnetic resonance imaging relaxometry.

Authors:  M H Teicher; C M Anderson; A Polcari; C A Glod; L C Maas; P F Renshaw
Journal:  Nat Med       Date:  2000-04       Impact factor: 53.440

Review 3.  The ecological validity of laboratory and analogue assessment methods of ADHD symptoms.

Authors:  R A Barkley
Journal:  J Abnorm Child Psychol       Date:  1991-04

4.  An objective measure of methylphenidate response: clinical use of the MCA.

Authors:  L M Greenberg
Journal:  Psychopharmacol Bull       Date:  1987

5.  Methylphenidate response in aggressive and nonaggressive ADHD children: distinctions on laboratory measures of symptoms.

Authors:  K Matier; J M Halperin; V Sharma; J H Newcorn; N Sathaye
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1992-03       Impact factor: 8.829

6.  Gender differences in children with ADHD, ODD, and co-occurring ADHD/ODD identified in a school population.

Authors:  C L Carlson; L Tamm; M Gaub
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1997-12       Impact factor: 8.829

7.  Trends in the prescribing of psychotropic medications to preschoolers.

Authors:  J M Zito; D J Safer; S dosReis; J F Gardner; M Boles; F Lynch
Journal:  JAMA       Date:  2000-02-23       Impact factor: 56.272

8.  Error patterns on the continuous performance test in non-medicated and medicated samples of children with and without ADHD: a meta-analytic review.

Authors:  B J Losier; P J McGrath; R M Klein
Journal:  J Child Psychol Psychiatry       Date:  1996-11       Impact factor: 8.982

9.  Impact of executive function deficits and attention-deficit/hyperactivity disorder (ADHD) on academic outcomes in children.

Authors:  Joseph Biederman; Michael C Monuteaux; Alysa E Doyle; Larry J Seidman; Timothy E Wilens; Frances Ferrero; Christie L Morgan; Stephen V Faraone
Journal:  J Consult Clin Psychol       Date:  2004-10

10.  Novel strategy for the analysis of CPT data provides new insight into the effects of methylphenidate on attentional states in children with ADHD.

Authors:  Martin H Teicher; Steven B Lowen; Ann Polcari; Mary Foley; Cynthia E McGreenery
Journal:  J Child Adolesc Psychopharmacol       Date:  2004       Impact factor: 2.576

View more
  8 in total

1.  Clinical gains from including both dextroamphetamine and methylphenidate in stimulant trials.

Authors:  Bjørn E Ramtvedt; Elisabeth Røinås; Henning S Aabech; Kjetil S Sundet
Journal:  J Child Adolesc Psychopharmacol       Date:  2013-05-09       Impact factor: 2.576

Review 2.  The clinical utility of the continuous performance test and objective measures of activity for diagnosing and monitoring ADHD in children: a systematic review.

Authors:  Charlotte L Hall; Althea Z Valentine; Madeleine J Groom; Gemma M Walker; Kapil Sayal; David Daley; Chris Hollis
Journal:  Eur Child Adolesc Psychiatry       Date:  2015-11-30       Impact factor: 4.785

3.  Utility of objective measures of activity and attention in the assessment of therapeutic response to stimulants in children with attention-deficit/hyperactivity disorder.

Authors:  Martin H Teicher; Ann Polcari; Cynthia E McGreenery
Journal:  J Child Adolesc Psychopharmacol       Date:  2008-06       Impact factor: 2.576

4.  Objective Measures of Behavior Manifestations in Adult ADHD and Differentiation from Participants with Bipolar II Disorder, Borderline Personality Disorder, Participants with Disconfirmed ADHD as Well as Normative Participants.

Authors:  Hanna Edebol; Lars Helldin; Torsten Norlander
Journal:  Clin Pract Epidemiol Ment Health       Date:  2012-11-02

5.  A preliminary study of movement intensity during a Go/No-Go task and its association with ADHD outcomes and symptom severity.

Authors:  Fenghua Li; Yi Zheng; Stephanie D Smith; Frederick Shic; Christina C Moore; Xixi Zheng; Yanjie Qi; Zhengkui Liu; James F Leckman
Journal:  Child Adolesc Psychiatry Ment Health       Date:  2016-12-12       Impact factor: 3.033

6.  The influence of participation in target-shooting sport for children with inattentive, hyperactive and impulsive symptoms - A controlled study of best practice.

Authors:  Annegrete Gohr Månsson; Mette Elmose; Søren Dalsgaard; Kirsten K Roessler
Journal:  BMC Psychiatry       Date:  2017-03-28       Impact factor: 3.630

7.  The Impact of Methylphenidate on QbTest Performance of Children with ADHD: A Retrospective Clinical Study.

Authors:  Rajna Knez; Dejan Stevanovic; Salmir Nasic; Ana Doric; Elisabet Wentz
Journal:  Neuropsychiatr Dis Treat       Date:  2021-01-06       Impact factor: 2.570

Review 8.  Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of adverse events in non-randomised studies.

Authors:  Ole Jakob Storebø; Nadia Pedersen; Erica Ramstad; Maja Lærke Kielsholm; Signe Sofie Nielsen; Helle B Krogh; Carlos R Moreira-Maia; Frederik L Magnusson; Mathilde Holmskov; Trine Gerner; Maria Skoog; Susanne Rosendal; Camilla Groth; Donna Gillies; Kirsten Buch Rasmussen; Dorothy Gauci; Morris Zwi; Richard Kirubakaran; Sasja J Håkonsen; Lise Aagaard; Erik Simonsen; Christian Gluud
Journal:  Cochrane Database Syst Rev       Date:  2018-05-09
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.