Literature DB >> 17452784

Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.

Philip Day1, Andrew Sharff, Lina Parra, Anne Cleasby, Mark Williams, Stefan Hörer, Herbert Nar, Norbert Redemann, Ian Tickle, Jeff Yon.   

Abstract

AMP-activated kinase (AMPK) is central to sensing energy status in eukaryotic cells via binding of AMP and ATP to CBS (cystathionine beta-synthase) domains in the regulatory gamma subunit. The structure of a CBS-domain pair from human AMPK gamma1 in complex with the physiological activator AMP and the pharmacological activator ZMP (AICAR) is presented.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17452784     DOI： 10.1107/S0907444907009110

Source DB:  PubMed          Journal:  Acta Crystallogr D Biol Crystallogr        ISSN： 0907-4449


  35 in total

1.  Unique gating properties of C. elegans ClC anion channel splice variants are determined by altered CBS domain conformation and the R-helix linker.

Authors:  Sonya Dave; Jonathan H Sheehan; Jens Meiler; Kevin Strange
Journal:  Channels (Austin)       Date:  2010-07-21       Impact factor: 2.581

2.  Crystallization and preliminary crystallographic analysis of merohedrally twinned crystals of MJ0729, a CBS-domain protein from Methanococcus jannaschii.

Authors:  Pablo Fernández-Millán; Danel Kortazar; María Lucas; María Luz Martínez-Chantar; Egoitz Astigarraga; José Andrés Fernández; Olatz Sabas; Armando Albert; Jose M Mato; Luis Alfonso Martínez-Cruz
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-06-07

3.  Purification, crystallization and preliminary X-ray diffraction analysis of the CBS-domain pair from the Methanococcus jannaschii protein MJ0100.

Authors:  María Lucas; Danel Kortazar; Egoitz Astigarraga; José A Fernández; Jose M Mato; María Luz Martínez-Chantar; Luis Alfonso Martínez-Cruz
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-09-30

4.  Purification, crystallization and preliminary crystallographic analysis of protein MJ1225 from Methanocaldococcus jannaschii, a putative archaeal homologue of gamma-AMPK.

Authors:  Inmaculada Gómez García; Danel Kortázar; Iker Oyenarte; José María Mato; María Luz Martínez-Chantar; Luis Alfonso Martínez-Cruz
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-07-30

5.  Purification, crystallization and preliminary X-ray diffraction analysis of a cystathionine beta-synthase domain-containing protein, CDCP2, from Arabidopsis thaliana.

Authors:  Byung Cheon Jeong; Kyoung Shin Yoo; Kwang Wook Jung; Jeong Sheop Shin; Hyun Kyu Song
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-08-20

6.  Increased transsulfuration mediates longevity and dietary restriction in Drosophila.

Authors:  Hadise Kabil; Omer Kabil; Ruma Banerjee; Lawrence G Harshman; Scott D Pletcher
Journal:  Proc Natl Acad Sci U S A       Date:  2011-09-19       Impact factor: 11.205

7.  Purification, crystallization and preliminary crystallographic analysis of the CBS-domain protein MJ1004 from Methanocaldococcus jannaschii.

Authors:  Iker Oyenarte; María Lucas; Inmaculada Gómez García; Luis Alfonso Martínez-Cruz
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2011-02-23

8.  Identification of yeast and human 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAr) transporters.

Authors:  Johanna Ceschin; Christelle Saint-Marc; Jean Laporte; Adrien Labriet; Chloé Philippe; Michel Moenner; Bertrand Daignan-Fornier; Benoît Pinson
Journal:  J Biol Chem       Date:  2014-04-28       Impact factor: 5.157

9.  Phosphorylation of hepatic AMP-activated protein kinase and liver kinase B1 is increased after a single oral dose of green tea extract to mice.

Authors:  Subhashis Banerjee; Sarbani Ghoshal; Todd D Porter
Journal:  Nutr Res       Date:  2012-11-20       Impact factor: 3.315

10.  Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.

Authors:  Simon A Hawley; Fiona A Ross; Cyrille Chevtzoff; Kevin A Green; Ashleigh Evans; Sarah Fogarty; Mhairi C Towler; Laura J Brown; Oluseye A Ogunbayo; A Mark Evans; D Grahame Hardie
Journal:  Cell Metab       Date:  2010-06-09       Impact factor: 27.287
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.