OBJECTIVE:Home screening tests could eliminate several barriers to testing sexually transmitted diseases (STDs). AIM: To determine whether offering repeated home screening tests would increase the rate of testing for chlamydia and gonorrhoea in a high-risk sample of young women. METHODS: In this randomised controlled trial, 403 young women (mean age 18.9 years, 70% black) with a recent STD or with STD-related risk factors were enrolled. Participants were recruited from clinics and high-prevalence neighbourhoods and then randomly assigned to receive either a home testing kit or an invitation to attend a medical clinic for testing at 6, 12 and 18 months after enrollment. Over 80% of women were followed for 2 years. The trial is registered with ClinicalTrials.gov, number NCT 00177437. RESULTS: Of 197 women in the intervention group, 140 (71%) returned at least one home test and 25 of 249 (10%) home tests were positive. Women who received home screening tests completed significantly more STD tests overall (1.94 vs 1.41 tests per woman-year, p<0.001) and more STD tests in the absence of symptoms (1.18 vs 0.75 tests per woman-year, p<0.001). More women in the intervention group completed at least one test when asymptomatic (162 (82.2%) vs 117 (61.3%), p<0.001). The intervention was most effective among women recruited outside medical clinics. There was no significant difference in the overall rate of STDs detected. CONCLUSIONS:Home screening significantly increased the utilisation of chlamydia and gonorrhoea testing in this sample of high-risk young women, and thus represents a feasible strategy to facilitate STD testing in young women.
RCT Entities:
OBJECTIVE: Home screening tests could eliminate several barriers to testing sexually transmitted diseases (STDs). AIM: To determine whether offering repeated home screening tests would increase the rate of testing for chlamydia and gonorrhoea in a high-risk sample of young women. METHODS: In this randomised controlled trial, 403 young women (mean age 18.9 years, 70% black) with a recent STD or with STD-related risk factors were enrolled. Participants were recruited from clinics and high-prevalence neighbourhoods and then randomly assigned to receive either a home testing kit or an invitation to attend a medical clinic for testing at 6, 12 and 18 months after enrollment. Over 80% of women were followed for 2 years. The trial is registered with ClinicalTrials.gov, number NCT 00177437. RESULTS: Of 197 women in the intervention group, 140 (71%) returned at least one home test and 25 of 249 (10%) home tests were positive. Women who received home screening tests completed significantly more STD tests overall (1.94 vs 1.41 tests per woman-year, p<0.001) and more STD tests in the absence of symptoms (1.18 vs 0.75 tests per woman-year, p<0.001). More women in the intervention group completed at least one test when asymptomatic (162 (82.2%) vs 117 (61.3%), p<0.001). The intervention was most effective among women recruited outside medical clinics. There was no significant difference in the overall rate of STDs detected. CONCLUSIONS: Home screening significantly increased the utilisation of chlamydia and gonorrhoea testing in this sample of high-risk young women, and thus represents a feasible strategy to facilitate STD testing in young women.
Authors: I G van Valkengoed; S A Morré; A J van den Brule; C J Meijer; W Devillé; L M Bouter; A J Boeke Journal: Sex Transm Infect Date: 2000-10 Impact factor: 3.519
Authors: Max A Chernesky; Edward W Hook; David H Martin; Jeannine Lane; Randy Johnson; Jeanne A Jordan; Deanna Fuller; Dean E Willis; Paul M Fine; William M Janda; Julius Schachter Journal: Sex Transm Dis Date: 2005-12 Impact factor: 2.830
Authors: Charlotte A Gaydos; Karen Dwyer; Mathilda Barnes; Patricia A Rizzo-Price; Billie Jo Wood; Toni Flemming; M Terry Hogan Journal: Sex Transm Dis Date: 2006-07 Impact factor: 2.830
Authors: Anna S Graseck; Gina M Secura; Jenifer E Allsworth; Tessa Madden; Jeffrey F Peipert Journal: Obstet Gynecol Date: 2010-12 Impact factor: 7.661
Authors: Charlotte A Gaydos; Mary Jett-Goheen; Mathilda Barnes; Laura Dize; Perry Barnes; Yu-Hsiang Hsieh Journal: Sex Transm Infect Date: 2015-08-18 Impact factor: 3.519
Authors: Jane R Schwebke; Jeannette Y Lee; Shelly Lensing; Susan S Philip; Harold C Wiesenfeld; Arlene C Seña; Nikole Trainor; Nincoshka Acevado; Lisa Saylor; Ann M Rompalo; Robert L Cook Journal: Clin Infect Dis Date: 2015-11-26 Impact factor: 9.079
Authors: Marcia M Hobbs; Barbara van der Pol; Patricia Totten; Charlotte A Gaydos; Anna Wald; Terri Warren; Rachel L Winer; Robert L Cook; Carolyn D Deal; M Elizabeth Rogers; Julius Schachter; King K Holmes; David H Martin Journal: Sex Transm Dis Date: 2008-01 Impact factor: 2.830
Authors: Charlotte A Gaydos; Mathilda R Barnes; Nicole Quinn; Mary Jett-Goheen; Yu-Hsiang Hsieh Journal: Sex Transm Infect Date: 2013-01-26 Impact factor: 3.519