Literature DB >> 17265305

TLC and HPLC analysis of Echinacea pallida and E. angustifolia roots.

R Bauer1, I A Khan, H Wagner.   

Abstract

The roots of ECHINACEA PALLIDA are characterized by TLC and HPLC fingerprints of the polyacetylenes, polyenes, and the caffeic acid derivatives. The fingerprints can also be used for the differentiation between E. PALLIDA and E. ANGUSTIFOLIA root extracts. The main constituents of E. PALLIDA roots are tetradeca-8 Z-ene-11,13-diyn-2-one ( 2), pentadeca-8 Z-ene-11,13-diyn-2-one ( 3), pentadeca-8 Z,13 Z-dien-11-yn-2-one ( 4), pentadeca-8 Z,11 Z,13 E-trien-2-one ( 5), pentadeca-8 Z,11 E,13 Z-trien-2-one ( 6), pentadeca-8 Z,11 Z-dien-2-one ( 7), and echinacoside ( 13). E. ANGUSTIFOLIA is usually void of these polyacetylenes and polyenes and is characterized by isobutylamides, echinacoside, and cynarine. The polyacetylenes of E. PALLIDA are very susceptible to autoxidation to the 8-hydroxy-9-ene derivatives. Thus, the chemical composition of the roots depends on the storage conditions.

Entities:  

Year:  1988        PMID： 17265305     DOI： 10.1055/s-2006-962489

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  9 in total

1.  Ineffectiveness of echinacea for prevention of experimental rhinovirus colds.

Authors:  R B Turner; D K Riker; J D Gangemi
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

2.  Need for additional, specific information in studies with echinacea.

Authors:  C Dennehy
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

3.  Alkamide stability in Echinacea purpurea extracts with and without phenolic acids in dry films and in solution.

Authors:  Yi Liu; Patricia A Murphy
Journal:  J Agric Food Chem       Date:  2007-01-10       Impact factor: 5.279

4.  Bauer ketones 23 and 24 from Echinacea paradoxa var. paradoxa inhibit lipopolysaccharide-induced nitric oxide, prostaglandin E2 and cytokines in RAW264.7 mouse macrophages.

Authors:  Xiaozhu Zhang; Ludmila Rizshsky; Catherine Hauck; Luping Qu; Mark P Widrlechner; Basil J Nikolau; Patricia A Murphy; Diane F Birt
Journal:  Phytochemistry       Date:  2011-11-29       Impact factor: 4.072

5.  Integrating metabolomics and transcriptomics data to discover a biocatalyst that can generate the amine precursors for alkamide biosynthesis.

Authors:  Ludmila Rizhsky; Huanan Jin; Michael R Shepard; Harry W Scott; Alicen M Teitgen; M Ann Perera; Vandana Mhaske; Adarsh Jose; Xiaobin Zheng; Matt Crispin; Eve S Wurtele; Dallas Jones; Manhoi Hur; Elsa Góngora-Castillo; C Robin Buell; Robert E Minto; Basil J Nikolau
Journal:  Plant J       Date:  2016-09-27       Impact factor: 6.417

6.  Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.

Authors:  Kevin Spelman; Matthew H Wetschler; Nadja B Cech
Journal:  J Pharm Biomed Anal       Date:  2009-02-20       Impact factor: 3.935

7.  Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida.

Authors:  A Chicca; F Pellati; B Adinolfi; A Matthias; I Massarelli; S Benvenuti; E Martinotti; A M Bianucci; K Bone; R Lehmann; P Nieri
Journal:  Br J Pharmacol       Date:  2008-01-14       Impact factor: 8.739

8.  Comparing the Effect of Echinacea and Chlorhexidine Mouthwash on the Microbial Flora of Intubated Patients Admitted to the Intensive Care Unit.

Authors:  Mehdi Safarabadi; Ehsanollah Ghaznavi-Rad; Abdolghader Pakniyat; Korosh Rezaie; Ali Jadidi
Journal:  Iran J Nurs Midwifery Res       Date:  2017 Nov-Dec

9.  In vitro and in vivo evaluation of antibacterial and anti-biofilm properties of five ethnomedicinal plants against oral bacteria by TEM.

Authors:  Fariba Fathi; Maryam Sadrnia; Mohammad Arjomandzadegan; Hamid Reza Mohajerani
Journal:  Avicenna J Phytomed       Date:  2021 Mar-Apr
  9 in total

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