Literature DB >> 10817735

Ineffectiveness of echinacea for prevention of experimental rhinovirus colds.

R B Turner1, D K Riker, J D Gangemi.   

Abstract

The purpose of this study was to assess the effectiveness of echinacea for the prevention of experimental rhinovirus colds. Infection occurred in 44 and 57% and illness occurred in 36 and 43% of the echinacea- and placebo-treated subjects, respectively. This preparation of echinacea had no significant effect on either the occurrence of infection or the severity of illness.

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Mesh：

Year:  2000        PMID： 10817735      PMCID： PMC89939          DOI： 10.1128/AAC.44.6.1708-1709.2000

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized, placebo controlled, double-blind clinical trial.

Authors:  R M Brinkeborn; D V Shah; F H Degenring
Journal:  Phytomedicine       Date:  1999-03       Impact factor: 5.340

2.  In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients.

Authors:  D M See; N Broumand; L Sahl; J G Tilles
Journal:  Immunopharmacology       Date:  1997-01

3.  Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase.

Authors:  W E Robinson; M G Reinecke; S Abdel-Malek; Q Jia; S A Chow
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

4.  Echinacea-induced cytokine production by human macrophages.

Authors:  R A Burger; A R Torres; R P Warren; V D Caldwell; B G Hughes
Journal:  Int J Immunopharmacol       Date:  1997-07

5.  Relation between naturally acquired immunity and infectivity of two rhinoviruses in volunteers.

Authors:  J O Hendley; W P Edmondson; J M Gwaltney
Journal:  J Infect Dis       Date:  1972-03       Impact factor: 5.226

6.  A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections.

Authors:  W Grimm; H H Müller
Journal:  Am J Med       Date:  1999-02       Impact factor: 4.965

7.  Dicaffeoylquinic and dicaffeoyltartaric acids are selective inhibitors of human immunodeficiency virus type 1 integrase.

Authors:  B McDougall; P J King; B W Wu; Z Hostomsky; M G Reinecke; W E Robinson
Journal:  Antimicrob Agents Chemother       Date:  1998-01       Impact factor: 5.191

8.  TLC and HPLC Analysis of Alkamides in Echinacea Drugs1,2.

Authors:  R Bauer; P Remiger
Journal:  Planta Med       Date:  1989-08       Impact factor: 3.352

9.  Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea.

Authors:  M Stimpel; A Proksch; H Wagner; M L Lohmann-Matthes
Journal:  Infect Immun       Date:  1984-12       Impact factor: 3.441

10.  Echinacea root extracts for the prevention of upper respiratory tract infections: a double-blind, placebo-controlled randomized trial.

Authors:  D Melchart; E Walther; K Linde; R Brandmaier; C Lersch
Journal:  Arch Fam Med       Date:  1998 Nov-Dec
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  24 in total

1.  Need for additional, specific information in studies with echinacea.

Authors:  C Dennehy
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

2.  Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension.

Authors:  Paula N Brown; Michael Chan; Lori Paley; Joseph M Betz
Journal:  J AOAC Int       Date:  2011 Sep-Oct       Impact factor: 1.913

Review 3.  Human rhinoviruses.

Authors:  Samantha E Jacobs; Daryl M Lamson; Kirsten St George; Thomas J Walsh
Journal:  Clin Microbiol Rev       Date:  2013-01       Impact factor: 26.132

4.  Echinacea for treating the common cold: a randomized trial.

Authors:  Bruce Barrett; Roger Brown; Dave Rakel; Marlon Mundt; Kerry Bone; Shari Barlow; Tola Ewers
Journal:  Ann Intern Med       Date:  2010-12-21       Impact factor: 25.391

Review 5.  The safety of herbal medicinal products derived from Echinacea species: a systematic review.

Authors:  Alyson L Huntley; Joanna Thompson Coon; Edzard Ernst
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

Review 6.  Echinacea for preventing and treating the common cold.

Authors:  Marlies Karsch-Völk; Bruce Barrett; David Kiefer; Rudolf Bauer; Karin Ardjomand-Woelkart; Klaus Linde
Journal:  Cochrane Database Syst Rev       Date:  2014-02-20

7.  Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial.

Authors:  Scott A Halperin; Bruce Smith; Coleen Nolan; Janet Shay; Jaroslav Kralovec
Journal:  CMAJ       Date:  2003-07-22       Impact factor: 8.262

8.  Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial.

Authors:  M Jawad; R Schoop; A Suter; P Klein; R Eccles
Journal:  Evid Based Complement Alternat Med       Date:  2012-09-16       Impact factor: 2.629

9.  Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice.

Authors:  Amira M K Abouelella; Yasser E Shahein; Sameh S Tawfik; Ahmed M Zahran
Journal:  J Vet Sci       Date:  2007-12       Impact factor: 1.672

Review 10.  Experimental Antiviral Therapeutic Studies for Human Rhinovirus Infections.

Authors:  James A Coultas; John Cafferkey; Patrick Mallia; Sebastian L Johnston
Journal:  J Exp Pharmacol       Date:  2021-07-09
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