Literature DB >> 17243586

An optimal three-class linear observer derived from decision theory.

Xin He1, Eric C Frey.   

Abstract

Many attempts have been made to develop an optimal linear observer for classifying multiclass data. Most approaches either do not have a definite description of optimality or have regions of ambiguity in decision making. In this paper, we derive a three-class Hotelling observer (3-HO), inspired by the ideal observer that results from a decision theoretic solution to the three-class classification problem. Assuming the data vectors follow multivariate Gaussian distributions with equal covariance matrices for the three classes, it is shown that two two-class Hotelling templates construct a 3-HO which has the same performance as the three-class ideal observer (3-IO). We show that, without the Gaussian and equal covariance assumptions, the 3-HO is still applicable when the two-class Hotelling templates of each pair of the classes satisfy a certain linear relationship. In this case, the 3-HO simultaneously maximizes the signal-to-noise (SNR) of the test statistics between each pair of the classes. In conclusion, we developed a three-class linear mathematical observer that uses first- and second-order ensemble data statistics. This mathematical observer, which has clearly defined optimality for several data statistics conditions and has decision rules that have no ambiguous decision regions, is potentially useful in the optimization and evaluation of imaging techniques for performing three-class diagnostic tasks.

Mesh:

Year:  2007        PMID: 17243586     DOI: 10.1109/TMI.2006.885335

Source DB:  PubMed          Journal:  IEEE Trans Med Imaging        ISSN: 0278-0062            Impact factor:   10.048


  7 in total

Review 1.  ROC analysis in medical imaging: a tutorial review of the literature.

Authors:  Charles E Metz
Journal:  Radiol Phys Technol       Date:  2007-10-27

2.  The meaning and use of the volume under a three-class ROC surface (VUS).

Authors:  Xin He; Eric C Frey
Journal:  IEEE Trans Med Imaging       Date:  2008-05       Impact factor: 10.048

3.  Three-class ROC analysis--toward a general decision theoretic solution.

Authors:  Xin He; Brandon D Gallas; Eric C Frey
Journal:  IEEE Trans Med Imaging       Date:  2009-10-30       Impact factor: 10.048

4.  Optimization and comparison of simultaneous and separate acquisition protocols for dual isotope myocardial perfusion SPECT.

Authors:  Michael Ghaly; Jonathan M Links; Eric C Frey
Journal:  Phys Med Biol       Date:  2015-06-17       Impact factor: 3.609

5.  Application of three-class ROC analysis to task-based image quality assessment of simultaneous dual-isotope myocardial perfusion SPECT (MPS).

Authors:  Xin He; Xiyun Song; Eric C Frey
Journal:  IEEE Trans Med Imaging       Date:  2008-11       Impact factor: 10.048

6.  Toward realistic and practical ideal observer (IO) estimation for the optimization of medical imaging systems.

Authors:  Xin He; Brian S Caffo; Eric C Frey
Journal:  IEEE Trans Med Imaging       Date:  2008-10       Impact factor: 10.048

7.  The validity of three-class Hotelling trace (3-HT) in describing three-class task performance: comparison of three-class volume under ROC surface (VUS) and 3-HT.

Authors:  Xin He; Eric C Frey
Journal:  IEEE Trans Med Imaging       Date:  2009-02       Impact factor: 10.048

  7 in total

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