Literature DB >> 17116684

Tolerance to the glycopeptides vancomycin and teicoplanin in coagulase-negative staphylococci.

Ingrid Bourgeois1, Martine Pestel-Caron, Jean-Francois Lemeland, Jean-Louis Pons, Francois Caron.   

Abstract

Tolerance to vancomycin and teicoplanin in 90 clinical isolates of coagulase-negative staphylococci (CoNS) was investigated by time-kill curve methodology. Only six strains, belonging to the Staphylococcus lugdunensis species, exhibited tolerance. The seven other S. lugdunensis strains tested displayed weak susceptibility to the bactericidal activity of glycopeptides compared to the other CoNS. These phenomena are of concern, since S. lugdunensis is recognized as one of the most pathogenic CoNS.

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Year:  2006        PMID： 17116684      PMCID： PMC1797755          DOI： 10.1128/AAC.00719-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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