| Literature DB >> 18367572 |
Cathy A Petti1, Keith E Simmon, Jose M Miro, Bruno Hoen, Francesc Marco, Vivian H Chu, Eugene Athan, Suzana Bukovski, Emilio Bouza, Suzanne Bradley, Vance G Fowler, Efthymia Giannitsioti, David Gordon, Porl Reinbott, Tony Korman, Selwyn Lang, Cristina Garcia-de-la-Maria, Annibale Raglio, Arthur J Morris, Patrick Plesiat, Suzanne Ryan, Thanh Doco-Lecompte, Francesca Tripodi, Riccardo Utili, Dannah Wray, J Jeffrey Federspiel, K Boisson, L Barth Reller, David R Murdoch, Christopher W Woods.
Abstract
Coagulase-negative staphylococci (CNS) are important causes of infective endocarditis (IE), but their microbiological profiles are poorly described. We performed DNA target sequencing and susceptibility testing for 91 patients with definite CNS IE who were identified from the International Collaboration on Endocarditis-Microbiology, a large, multicenter, multinational consortium. A hierarchy of gene sequences demonstrated great genetic diversity within CNS from patients with definite endocarditis that represented diverse geographic regions. In particular, rpoB sequence data demonstrated unique genetic signatures with the potential to serve as an important tool for global surveillance.Entities:
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Year: 2008 PMID： 18367572 PMCID： PMC2395089 DOI： 10.1128/JCM.02405-07
Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948