| Literature DB >> 170810 |
D A Willoughby, C J Dunn, S Yamamoto, F Capasso, D A Deporter, J P Giroud.
Abstract
A model is described of acute inflammation in the pleural cavity of rats using calcium pyrophosphate as the irritant. This model would seem to simulate the pseudogout syndrome. It has been shown to be acute in onset, dominated by polymorphonuclear cells, complement independent. The advantage of the model is that volume of exudate, numbers and types of cells may be quantitated. Prostaglandins and cyclic AMP have been measured in the migrating cells. The significance of these findings has been discussed.Entities:
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Year: 1975 PMID： 170810 DOI： 10.1007/bf02027156
Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299