Literature DB >> 181970

Anti-inflammatory models in animals.

D A Willoughby, P Dieppe.   

Abstract

The pleural cavity of rats and guinea-pigs has been utilized to study the inflammatory response to immediate hypersensitivity, delayed hypersensitivity, calcium pyrophosphate and carrageenan. The mediators will be described and their possible interaction with cyclic AMP. Finally the effect of some anti-inflammatory agents on these models will be discussed.

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Year:  1976        PMID： 181970     DOI： 10.1007/bf01972247

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  7 in total

1.  Heberden Oration, 1974. Human arthritis applied to animal models. Towards a better therapy.

Authors:  D A Willoughby
Journal:  Ann Rheum Dis       Date:  1975-12       Impact factor: 19.103

2.  Quantitative studies on cell-mediated immunity in the pleural cavity of guinea-pigs.

Authors:  S Yamamoto; C J Dunn; F Capasso; D A Deporter; D A Willoughby
Journal:  J Pathol       Date:  1975-10       Impact factor: 7.996

3.  Pharmacological mediators of various immunological and non-immunological inflammatory reactions produced in the pleural cavity.

Authors:  F Capasso; C J Dunn; S Yamamoto; D A Deporter; J P Giroud; D A Willoughby
Journal:  Agents Actions       Date:  1975-12

4.  Immunologic models used for the study of rheumatoid arthritis.

Authors:  H E Jasin; T D Cooke; E R Hurd; J D Smiley; M Ziff
Journal:  Fed Proc       Date:  1973-02

5.  The pharmaco-cellular assessment of slow acting anti-inflammatory agents.

Authors:  J P Giroud; W G Spector; J Timsit; D A Willoughby
Journal:  Agents Actions       Date:  1973-11

6.  Calcium pyrophosphate-induced pleurisy in rats: a new model of acute inflammation.

Authors:  D A Willoughby; C J Dunn; S Yamamoto; F Capasso; D A Deporter; J P Giroud
Journal:  Agents Actions       Date:  1975-02

7.  A physiologic differentiation between delayed and immediate hypersensitivity.

Authors:  M A Apicella; J C Allen
Journal:  J Clin Invest       Date:  1969-02       Impact factor: 14.808
  7 in total
  1 in total

1.  Professor Derek Albert Willoughby (1930-2004).

Authors:  K D Rainsford
Journal:  Inflammopharmacology       Date:  2005       Impact factor: 4.473
  1 in total

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