Literature DB >> 130792

Pharmacological mediators of various immunological and non-immunological inflammatory reactions produced in the pleural cavity.

F Capasso, C J Dunn, S Yamamoto, D A Deporter, J P Giroud, D A Willoughby.   

Abstract

Intrapleural exudates have been produced in rats and guinea-pigs using calcium pyrophosphate, cell mediated immunity, reversed passive Arthus reaction and carrageenan. The intracellular concentration of various pharmacological mediators has been measured at different times during the evolution of these inflammatory responses. These have been correlated with volume of exudate and cellular migration. The significance of these findings has been discussed and the possible application to the search for new anti-inflammatory agents and their use in diagnostic procedures.

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Year:  1975        PMID： 130792     DOI： 10.1007/bf01972690

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  7 in total

1.  Heberden Oration, 1974. Human arthritis applied to animal models. Towards a better therapy.

Authors:  D A Willoughby
Journal:  Ann Rheum Dis       Date:  1975-12       Impact factor: 19.103

2.  Quantitative studies on cell-mediated immunity in the pleural cavity of guinea-pigs.

Authors:  S Yamamoto; C J Dunn; F Capasso; D A Deporter; D A Willoughby
Journal:  J Pathol       Date:  1975-10       Impact factor: 7.996

3.  Further studies on carrageenan-induced pleurisy in rats.

Authors:  F Capasso; C J Dunn; S Yamamoto; D A Willoughby; J P Giroud
Journal:  J Pathol       Date:  1975-06       Impact factor: 7.996

4.  Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine.

Authors:  M Di Rosa; J P Giroud; D A Willoughby
Journal:  J Pathol       Date:  1971-05       Impact factor: 7.996

5.  Distribution of prostaglandins in inflammatory exudate.

Authors:  G P Velo; C J Dunn; J P Giroud; J Timsit; D A Willoughby
Journal:  J Pathol       Date:  1973-11       Impact factor: 7.996

6.  Calcium pyrophosphate-induced pleurisy in rats: a new model of acute inflammation.

Authors:  D A Willoughby; C J Dunn; S Yamamoto; F Capasso; D A Deporter; J P Giroud
Journal:  Agents Actions       Date:  1975-02

7.  Cutaneous reactions to intradermal prostaglandins.

Authors:  P Crunkhorn; A L Willis
Journal:  Br J Pharmacol       Date:  1971-01       Impact factor: 8.739
  7 in total
  8 in total

1.  Professor Derek Albert Willoughby (1930-2004).

Authors:  K D Rainsford
Journal:  Inflammopharmacology       Date:  2005       Impact factor: 4.473

2.  Anti-inflammatory models in animals.

Authors:  D A Willoughby; P Dieppe
Journal:  Agents Actions       Date:  1976-02

3.  Prostaglandin F2alpha produced by inducible cyclooxygenase may contribute to the resolution of inflammation.

Authors:  Paul R Colville-Nash; Derek W Gilroy; Dean Willis; Mark J Paul-Clark; Adrian R Moore; Derek A Willoughby
Journal:  Inflammopharmacology       Date:  2005       Impact factor: 4.473

4.  The reactivity of neutrophils at the site of an acute inflammatory reaction as measured by chemiluminescence.

Authors:  J Bird; J P Giroud
Journal:  Agents Actions       Date:  1984-10

5.  Phenyl isothiocyanate pleurisy in rats--a model for the evaluation of anti-exudative substances.

Authors:  M Rothkopf-Ischebeck
Journal:  Agents Actions       Date:  1978-12

Review 6.  Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases.

Authors:  Gye Young Park; John W Christman
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2006-05       Impact factor: 5.464

7.  Prostacyclin and thromboxanes in carrageenan-induced pleurisy in the rat.

Authors:  M Tissot; C Bonne; B Martin; M Solier; J P Giroud
Journal:  Agents Actions       Date:  1984-01

8.  A comparison of air pouch, sponge and pleurisy models of acute carrageenan inflammation in the rat.

Authors:  A D Sedgwick; P Lees
Journal:  Agents Actions       Date:  1986-06
  8 in total

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