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Literature DB >> 170358

Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages.

Abstract

Peritoneal macrophages from mice infected with Bacille Calmette-Guérin (BCG) and from normal mice were examined for their effects in vitro on thymidine uptake by 10 murine lymphomas, a murine fibroblast line, and a guinea pig hepatoma. Only the murine fibroblast line showed growth inhibition in the presence of BCG macrophages. For the majority of tumors, normal macrophages were profoundly stimulatory to tumor cell DNA synthesis, while BCG macrophages were much less stimulatory, without being frankly inhibitory. The effect of 2-mercaptoethanol on tumor cell growth was also studied. All lymphomas stimulated to grow more rapidly in vitro by normal macrophages were stimulated to a similar degree by 2-mercaptoethanol.

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Year: 1975 PMID： 170358 PMCID： PMC2189947 DOI： 10.1084/jem.142.4.887

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

48 in total

1. Activation of human blood monocytes by products of sensitized lymphocytes.

Authors: R E Rocklin; C T Winston; J R David
Journal: J Clin Invest Date: 1974-02 Impact factor: 14.808

2. Major changes in lymphocyte proliferation evoked by activated macrophages.

Authors: R Keller
Journal: Cell Immunol Date: 1975-06 Impact factor: 4.868

3. Allogeneic recognition and killing capacity of immune macrophages in mixed macrophage cultures (MMC).

Authors: R Gallily
Journal: Cell Immunol Date: 1975-02 Impact factor: 4.868

4. HOMOGRAFT TARGET CELLS: SPECIFIC DESTRUCTION IN VITRO BY CONTACT INTERACTION WITH IMMUNE MACROPHAGES.

Authors: G A GRANGER; R S WEISER
Journal: Science Date: 1964-09-25 Impact factor: 47.728

5. Effect of BCG infection on leukemia and polyoma in mice and hamsters.

Authors: P LEMONDE; M CLODE
Journal: Proc Soc Exp Biol Med Date: 1962-12

6. The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system.

Authors: J M KISSANE; E ROBINS
Journal: J Biol Chem Date: 1958-07 Impact factor: 5.157

7. Two biological activities regulating cell proliferation found in cultures of peritoneal exudate cells.

Authors: J Calderon; E R Unanue
Journal: Nature Date: 1975-01-31 Impact factor: 49.962

8. [Non specific active immunotherapy by B.C.G. in virus induced leukemia in E male G2 mice in isogenic receiptients].

Authors: J L Amiel
Journal: Rev Fr Etud Clin Biol Date: 1967-11

9. Macrophage cytotoxicity in the mouse immune response against a skin allograft.

Authors: A Dimitriu; M Dy; N Thomson; J Hamburger
Journal: J Immunol Date: 1975-01 Impact factor: 5.422

10. Inhibition of proliferation of lymphoma cells and T lymphocytes by suppressor cells from spleens of tumor-bearing mice.

Authors: H Kirchner; A V Muchmore; T M Chused; H T Holden; R B Herberman
Journal: J Immunol Date: 1975-01 Impact factor: 5.422

25 in total

10. Inhibition of lymphocyte mitogenesis by factor(s) released from macrophages isolated from ascitic fluid of advanced ovarian cancer patients.

Authors: B Sheid; J Boyce
Journal: Cancer Immunol Immunother Date: 1984 Impact factor: 6.968

Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages.

1. Activation of human blood monocytes by products of sensitized lymphocytes.

2. Major changes in lymphocyte proliferation evoked by activated macrophages.

3. Allogeneic recognition and killing capacity of immune macrophages in mixed macrophage cultures (MMC).

4. HOMOGRAFT TARGET CELLS: SPECIFIC DESTRUCTION IN VITRO BY CONTACT INTERACTION WITH IMMUNE MACROPHAGES.

5. Effect of BCG infection on leukemia and polyoma in mice and hamsters.

6. The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system.

7. Two biological activities regulating cell proliferation found in cultures of peritoneal exudate cells.

8. [Non specific active immunotherapy by B.C.G. in virus induced leukemia in E male G2 mice in isogenic receiptients].

9. Macrophage cytotoxicity in the mouse immune response against a skin allograft.

10. Inhibition of proliferation of lymphoma cells and T lymphocytes by suppressor cells from spleens of tumor-bearing mice.

1. A journey in science: promise, purpose, privilege.

2. Peritoneal macrophages from adjuvant arthritic rats enhance tumour cell growth in vitro.

3. Macrophage activation by tuftsin and muramyl-dipeptide.

4. Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.

Review 5. The human tumor cloning assay in cancer drug development. A review.

Review 6. Beyond oxidative stress: an immunologist's guide to reactive oxygen species.

7. Phagocytosis of Cryptococcus neoformans by normal and thioglycolate-activated macrophages.

8. Defective recognitive immunity in family aggregates of colon carcinoma.

9. Production of autoinhibitory factors by mouse lymphoma cells in vitro and its relationship to thiol dependence.

10. Inhibition of lymphocyte mitogenesis by factor(s) released from macrophages isolated from ascitic fluid of advanced ovarian cancer patients.