| Literature DB >> 11344570 |
R E Rocklin1, C T Winston, J R David.
Abstract
Studies were carried out to determine whether products of activated human lymphocytes altered human monocyte function. Supernatants from sensitized human lymphocytes stimulated by specific antigen were cultured with monolayers of human monocytes. Such monocytes exhibited enhanced adherence to their culture vessels and increased glucose carbon-1 oxidation after 2-3 days of incubation. The substance responsible for these effects was found to elute from Sephadex G-100 gel columns in a fraction with 23,000 mol wt, the same fraction containing human migration inhibitory factor.Entities:
Mesh:
Substances:
Year: 1974 PMID: 11344570 PMCID: PMC301499 DOI: 10.1172/JCI107590
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808