Literature DB >> 19129413

Melting curve analysis for rapid detection of topoisomerase gene mutations in Haemophilus influenzae.

Shigeki Nakamura1, Katsunori Yanagihara, Yoshitomo Morinaga, Koichi Izumikawa, Masafumi Seki, Hiroshi Kakeya, Yoshihiro Yamamoto, Shimeru Kamihira, Shigeru Kohno.   

Abstract

We established a real-time PCR assay with melting curve analysis to rapidly genotype quinolone resistance-determining regions (QRDRs) of gyrase A and topoisomerase IV genes in Haemophilus influenzae. This assay is a useful tool for the detection of fluoroquinolone resistance and for the early detection of preexisting QRDR mutations.

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Year:  2009        PMID： 19129413      PMCID： PMC2650933          DOI： 10.1128/JCM.01645-08

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  24 in total

Review 1.  The mutant selection window and antimicrobial resistance.

Authors:  Karl Drlica
Journal:  J Antimicrob Chemother       Date:  2003-06-12       Impact factor: 5.790

2.  Quinolone-resistant Haemophilus influenzae: determination of mutant selection window for ciprofloxacin, garenoxacin, levofloxacin, and moxifloxacin.

Authors:  Xinying Li; Noriel Mariano; James J Rahal; Carl M Urban; Karl Drlica
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

3.  Ciprofloxacin pharmacokinetics in young cystic fibrosis patients after repeated oral doses.

Authors:  F Odoul; C Le Guellec; C Giraut; C de Gialluly; S Marchand; G Paintaud; M C Saux; J C Rolland; E Autret-Leca
Journal:  Therapie       Date:  2001 Sep-Oct       Impact factor: 2.070

4.  Multiple-dose pharmacokinetics of ciprofloxacin administered intravenously to normal volunteers.

Authors:  M A Gonzalez; A H Moranchel; S Duran; A Pichardo; J L Magana; B Painter; A Forrest; G L Drusano
Journal:  Antimicrob Agents Chemother       Date:  1985-08       Impact factor: 5.191

5.  Quinolone-resistant Haemophilus influenzae in a long-term-care facility: nucleotide sequence characterization of alterations in the genes encoding DNA gyrase and DNA topoisomerase IV.

Authors:  Xinying Li; Noriel Mariano; James J Rahal; Carl M Urban; Karl Drlica
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

6.  Laboratory detection of Haemophilus influenzae with decreased susceptibility to nalidixic acid, ciprofloxacin, levofloxacin, and moxifloxacin due to GyrA and ParC mutations.

Authors:  María Pérez-Vázquez; Federico Román; Belén Aracil; Rafael Cantón; José Campos
Journal:  J Clin Microbiol       Date:  2004-03       Impact factor: 5.948

7.  Five-year analysis of Haemophilus influenzae isolates with reduced susceptibility to fluoroquinolones: prevalence results from the SENTRY antimicrobial surveillance program.

Authors:  Douglas J Biedenbach; Ronald N Jones
Journal:  Diagn Microbiol Infect Dis       Date:  2003-05       Impact factor: 2.803

8.  Levofloxacin treatment failure in Haemophilus influenzae pneumonia.

Authors:  Teresa Bastida; María Pérez-Vázquez; José Campos; María Cristina Cortés-Lletget; Federico Román; Fe Tubau; Adela G de la Campa; Carles Alonso-Tarrés
Journal:  Emerg Infect Dis       Date:  2003-11       Impact factor: 6.883

9.  Emergence of fluoroquinolone-resistant Haemophilus influenzae strains among elderly patients but not among children.

Authors:  Shin-ichi Yokota; Yasuo Ohkoshi; Kiyoshi Sato; Nobuhiro Fujii
Journal:  J Clin Microbiol       Date:  2007-10-31       Impact factor: 5.948

10.  Quinolone-resistant Haemophilus influenzae in a long-term care facility: clinical and molecular epidemiology.

Authors:  Jawad Nazir; Carl Urban; Noriel Mariano; Janice Burns; Barbara Tommasulo; Carl Rosenberg; Sorana Segal-Maurer; James J Rahal
Journal:  Clin Infect Dis       Date:  2004-05-12       Impact factor: 9.079
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  2 in total

1.  High-resolution melt curve analysis for identification of single nucleotide mutations in the quinolone resistance gene aac(6')-Ib-cr.

Authors:  Carlos Hidalgo-Grass; Jacob Strahilevitz
Journal:  Antimicrob Agents Chemother       Date:  2010-05-24       Impact factor: 5.191

2.  Molecular characterization of fluoroquinolone resistance in nontypeable Haemophilus influenzae clinical isolates.

Authors:  Carmen Puig; José Manuel Tirado-Vélez; Laura Calatayud; Fe Tubau; Junkal Garmendia; Carmen Ardanuy; Sara Marti; Adela G de la Campa; Josefina Liñares
Journal:  Antimicrob Agents Chemother       Date:  2014-11-10       Impact factor: 5.191
  2 in total

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