Multidetector CT (64 Slices) of the liver: examination techniques.

Sixty-four-row MDCT, although developed primarily for cardiac imaging, has the potential to have a great impact on liver imaging as well. Liver-imaging protocols with sub-millimeter collimation improve longitudinal spatial resolution, making the acquired dataset a real isotropic volume perfectly designed for optimal three-dimensional rendering and accurate organ and lesion volumetry. The 64-row detector array offers a wide volumetric coverage (up to 40 mm), suitable not only for shortening scanning time and improving spatial resolution, but also for including a large volume per single rotation, particularly useful for accurate CT perfusion studies. In order to take full benefit from the enormous performance offered by new 64-row MDCT scanners, imaging protocols need to be redesigned. Due to the extremely short scanning window, contrast agent injection should be performed at high flow rate and followed by saline bolus chaser; the use of highly concentrated contrast media might be useful. Timing should be accurately calculated either by a test bolus or, better, by using an automatic bolus-detection technique. Radiation exposure is kept under control, using automatic device-modulating dose delivery according to the patient's anatomy. Finally, the evaluation of acquired volumetric datasets needs the extensive use of a dedicated workstation, with software with sophisticated rendering capabilities.