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Literature DB >> 17007405

Rapid synthesis of diketopiperazine macroarrays via Ugi four-component reactions on planar solid supports.

Abstract

Libraries of diketopiperazines have been generated in high purity using the small molecule macroarray synthesis platform.

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 17007405 PMCID： PMC1761689 DOI： 10.1039/b604329a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

13 in total

Review 1. New tools and concepts for modern organic synthesis.

Authors: Steven V Ley; Ian R Baxendale
Journal: Nat Rev Drug Discov Date: 2002-08 Impact factor: 84.694

2. Generating diverse skeletons of small molecules combinatorially.

Authors: Martin D Burke; Eric M Berger; Stuart L Schreiber
Journal: Science Date: 2003-10-24 Impact factor: 47.728

3. Out of the oil bath and into the oven--microwave-assisted combinatorial chemistry heats up.

Authors: Helen E Blackwell
Journal: Org Biomol Chem Date: 2003-04-21 Impact factor: 3.876

4. Microwave-accelerated SPOT-synthesis on cellulose supports.

Authors: Matthew D Bowman; Ryan C Jeske; Helen E Blackwell
Journal: Org Lett Date: 2004-06-10 Impact factor: 6.005

5. Comprehensive survey of combinatorial library synthesis: 2004.

Authors: Roland E Dolle
Journal: J Comb Chem Date: 2005 Nov-Dec

6. Small molecule inhibitors of bacterial quorum sensing and biofilm formation.

Authors: Grant D Geske; Rachel J Wezeman; Adam P Siegel; Helen E Blackwell
Journal: J Am Chem Soc Date: 2005-09-21 Impact factor: 15.419

Review 7. The impact of microwave synthesis on drug discovery.

Authors: C Oliver Kappe; Doris Dallinger
Journal: Nat Rev Drug Discov Date: 2006-01 Impact factor: 84.694

8. Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays.

Authors: Matthew D Bowman; Megan M Jacobson; Helen E Blackwell
Journal: Org Lett Date: 2006-04-13 Impact factor: 6.005

9. New planar substrates for the in situ synthesis of peptide arrays.

Authors: Norbert Zander
Journal: Mol Divers Date: 2004 Impact factor: 2.943

10. Plant growth-promoting Pseudomonas putida WCS358 produces and secretes four cyclic dipeptides: cross-talk with quorum sensing bacterial sensors.

Authors: Giuliano Degrassi; Claudio Aguilar; Marco Bosco; Sotir Zahariev; Sandor Pongor; Vittorio Venturi
Journal: Curr Microbiol Date: 2002-10 Impact factor: 2.188

12 in total

Review 1. Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors: C Oliver Kappe; Doris Dallinger
Journal: Mol Divers Date: 2009-04-21 Impact factor: 2.943

2. Rethinking screening.

Authors: Thomas Kodadek
Journal: Nat Chem Biol Date: 2010-03 Impact factor: 15.040

3. Small molecule macroarray construction via palladium-mediated carbon-carbon bond-forming reactions: highly efficient synthesis and screening of stilbene arrays.

Authors: Reto Frei; Helen E Blackwell
Journal: Chemistry Date: 2010-03-01 Impact factor: 5.236

4. Efficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeri.

Authors: Jennifer Campbell; Helen E Blackwell
Journal: J Comb Chem Date: 2009 Nov-Dec

Review 5. Solid-phase and microwave-assisted syntheses of 2,5-diketopiperazines: small molecules with great potential.

Authors: Jennifer C O'Neill; Helen E Blackwell
Journal: Comb Chem High Throughput Screen Date: 2007-12 Impact factor: 1.339

6. N-phenylacetanoyl-L-homoserine lactones can strongly antagonize or superagonize quorum sensing in Vibrio fischeri.

Authors: Grant D Geske; Jennifer C O'Neill; Helen E Blackwell
Journal: ACS Chem Biol Date: 2007-05-04 Impact factor: 5.100

7. New and unexpected insights into the modulation of LuxR-type quorum sensing by cyclic dipeptides.

Authors: Jennifer Campbell; Qi Lin; Grant D Geske; Helen E Blackwell
Journal: ACS Chem Biol Date: 2009-12-18 Impact factor: 5.100

8. Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.

Authors: Grant D Geske; Jennifer C O'Neill; David M Miller; Margrith E Mattmann; Helen E Blackwell
Journal: J Am Chem Soc Date: 2007-10-10 Impact factor: 15.419

9. Chemical methods to interrogate bacterial quorum sensing pathways.

Authors: Thanit Praneenararat; Andrew G Palmer; Helen E Blackwell
Journal: Org Biomol Chem Date: 2012-10-03 Impact factor: 3.876

10. Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing.

Authors: Reto Frei; Anthony S Breitbach; Helen E Blackwell
Journal: Chem Sci Date: 2012-05 Impact factor: 9.825