Literature DB >> 16597131

Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays.

Matthew D Bowman1, Megan M Jacobson, Helen E Blackwell.   

Abstract

[structure: see text] Small molecule macroarrays of cyanopyridines and deazalumazines were generated in high purities via spatially addressed synthesis on planar cellulose supports. Examination of the spectral properties of the heterocycles both on and off of the planar support revealed a set of promising new fluorescent dyes that exhibit high quantum yields, low pH dependence, and high sensitivity to solvent polarity.

Entities:  

Year:  2006        PMID： 16597131     DOI： 10.1021/ol0602708

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

Review 1.  Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors:  C Oliver Kappe; Doris Dallinger
Journal:  Mol Divers       Date:  2009-04-21       Impact factor: 2.943

2.  Rapid synthesis of diketopiperazine macroarrays via Ugi four-component reactions on planar solid supports.

Authors:  Qi Lin; Helen E Blackwell
Journal:  Chem Commun (Camb)       Date:  2006-07-21       Impact factor: 6.222

3.  Small molecule macroarray construction via palladium-mediated carbon-carbon bond-forming reactions: highly efficient synthesis and screening of stilbene arrays.

Authors:  Reto Frei; Helen E Blackwell
Journal:  Chemistry       Date:  2010-03-01       Impact factor: 5.236

Review 4.  Screening strategies for quorum sensing inhibitors in combating bacterial infections.

Authors:  Lan Lu; Mingxing Li; Guojuan Yi; Li Liao; Qiang Cheng; Jie Zhu; Bin Zhang; Yingying Wang; Yong Chen; Ming Zeng
Journal:  J Pharm Anal       Date:  2021-04-02

5.  Efficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeri.

Authors:  Jennifer Campbell; Helen E Blackwell
Journal:  J Comb Chem       Date:  2009 Nov-Dec

6.  Chemical methods to interrogate bacterial quorum sensing pathways.

Authors:  Thanit Praneenararat; Andrew G Palmer; Helen E Blackwell
Journal:  Org Biomol Chem       Date:  2012-10-03       Impact factor: 3.876

7.  Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing.

Authors:  Reto Frei; Anthony S Breitbach; Helen E Blackwell
Journal:  Chem Sci       Date:  2012-05       Impact factor: 9.825

8.  Exploiting a multicomponent domino reaction strategy for the tailoring of versatile environmentally sensitive fluorophore-based nicotinonitriles incorporating pyrene and fluorene moieties.

Authors:  Essam M Hussein; Nizar El Guesmi; Saleh A Ahmed
Journal:  RSC Adv       Date:  2019-12-03       Impact factor: 4.036

9.  Rapid Discovery and Structure-Property Relationships of Metal-Ion Fluorescent Sensors via Macroarray Synthesis.

Authors:  Apiwat Promchat; Kanet Wongravee; Mongkol Sukwattanasinitt; Thanit Praneenararat
Journal:  Sci Rep       Date:  2019-07-17       Impact factor: 4.379

10.  Raman spectroscopy as a tool for monitoring mesoscale continuous-flow organic synthesis: Equipment interface and assessment in four medicinally-relevant reactions.

Authors:  Trevor A Hamlin; Nicholas E Leadbeater
Journal:  Beilstein J Org Chem       Date:  2013-09-11       Impact factor: 2.883
  10 in total

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