Literature DB >> 15176808

Microwave-accelerated SPOT-synthesis on cellulose supports.

Matthew D Bowman1, Ryan C Jeske, Helen E Blackwell.   

Abstract

[reaction: see text] We demonstrate that microwave irradiation can dramatically accelerate reaction rates for spatially addressable library synthesis on planar membrane supports. The development of a robust support/linker system, microwave-assisted synthesis of small molecule test libraries, and methods for solid-phase scale-up on cellulose are described.

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Year:  2004        PMID: 15176808     DOI: 10.1021/ol049313f

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  11 in total

Review 1.  Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors:  C Oliver Kappe; Doris Dallinger
Journal:  Mol Divers       Date:  2009-04-21       Impact factor: 2.943

2.  Microwave-Facilitated SPOT-Synthesis of Antibacterial Dipeptoids.

Authors:  Anne C Schneider; Daniel Fritz; Joseph K Vasquez; Sidonie B L Vollrath; Helen E Blackwell; Stefan Bräse
Journal:  ACS Comb Sci       Date:  2017-11-07       Impact factor: 3.784

3.  Rapid synthesis of diketopiperazine macroarrays via Ugi four-component reactions on planar solid supports.

Authors:  Qi Lin; Helen E Blackwell
Journal:  Chem Commun (Camb)       Date:  2006-07-21       Impact factor: 6.222

4.  Efficient construction of diketopiperazine macroarrays through a cyclative-cleavage strategy and their evaluation as luminescence inhibitors in the bacterial symbiont Vibrio fischeri.

Authors:  Jennifer Campbell; Helen E Blackwell
Journal:  J Comb Chem       Date:  2009 Nov-Dec

5.  Efficient synthesis and evaluation of quorum-sensing modulators using small molecule macroarrays.

Authors:  Thanit Praneenararat; Grant D Geske; Helen E Blackwell
Journal:  Org Lett       Date:  2009-10-15       Impact factor: 6.005

6.  Chemical methods to interrogate bacterial quorum sensing pathways.

Authors:  Thanit Praneenararat; Andrew G Palmer; Helen E Blackwell
Journal:  Org Biomol Chem       Date:  2012-10-03       Impact factor: 3.876

7.  Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing.

Authors:  Reto Frei; Anthony S Breitbach; Helen E Blackwell
Journal:  Chem Sci       Date:  2012-05       Impact factor: 9.825

8.  Multizone paper platform for 3D cell cultures.

Authors:  Ratmir Derda; Sindy K Y Tang; Anna Laromaine; Bobak Mosadegh; Estrella Hong; Martin Mwangi; Akiko Mammoto; Donald E Ingber; George M Whitesides
Journal:  PLoS One       Date:  2011-05-06       Impact factor: 3.240

9.  Rapid Discovery and Structure-Property Relationships of Metal-Ion Fluorescent Sensors via Macroarray Synthesis.

Authors:  Apiwat Promchat; Kanet Wongravee; Mongkol Sukwattanasinitt; Thanit Praneenararat
Journal:  Sci Rep       Date:  2019-07-17       Impact factor: 4.379

Review 10.  Recent Small-Molecule Inhibitors of the p53-MDM2 Protein-Protein Interaction.

Authors:  Anastasia Beloglazkina; Nikolai Zyk; Alexander Majouga; Elena Beloglazkina
Journal:  Molecules       Date:  2020-03-07       Impact factor: 4.411

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