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Literature DB >> 17001093

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.

A Beteva¹, F Cipriani, S Cusack, S Delageniere, J Gabadinho, E J Gordon, M Guijarro, D R Hall, S Larsen, L Launer, C B Lavault, G A Leonard, T Mairs, A McCarthy, J McCarthy, J Meyer, E Mitchell, S Monaco, D Nurizzo, P Pernot, R Pieritz, R G B Ravelli, V Rey, W Shepard, D Spruce, D I Stuart, O Svensson, P Theveneau, X Thibault, J Turkenburg, M Walsh, S M McSweeney.

Abstract

An automatic data-collection system has been implemented and installed on seven insertion-device beamlines and a bending-magnet beamline at the ESRF (European Synchrotron Radiation Facility) as part of the SPINE (Structural Proteomics In Europe) development of an automated structure-determination pipeline. The system allows remote interaction with beamline-control systems and automatic sample mounting, alignment, characterization, data collection and processing. Reports of all actions taken are available for inspection via database modules and web services.

Entities: Chemical

Mesh：

Year: 2006 PMID： 17001093 DOI： 10.1107/S0907444906032859

Source DB: PubMed Journal: Acta Crystallogr D Biol Crystallogr ISSN： 0907-4449

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Cited

28 in total

Review 1. Automated robotic harvesting of protein crystals-addressing a critical bottleneck or instrumentation overkill?

Authors: Robert Viola; Peter Carman; Jace Walsh; Daniel Frankel; Bernhard Rupp
Journal: J Struct Funct Genomics Date: 2007-10-27

2. First experiences with semi-autonomous robotic harvesting of protein crystals.

Authors: Robert Viola; Jace Walsh; Alex Melka; Wesley Womack; Sean Murphy; Alan Riboldi-Tunnicliffe; Bernhard Rupp
Journal: J Struct Funct Genomics Date: 2011-03-23

3. Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course.

Authors: Kyle M Stiers; Christopher B Lee; Jay C Nix; John J Tanner; Lesa J Beamer
Journal: J Appl Crystallogr Date: 2016-11-24 Impact factor: 3.304

Review 4. Cryo-EM in drug discovery: achievements, limitations and prospects.

Authors: Jean-Paul Renaud; Ashwin Chari; Claudio Ciferri; Wen-Ti Liu; Hervé-William Rémigy; Holger Stark; Christian Wiesmann
Journal: Nat Rev Drug Discov Date: 2018-06-08 Impact factor: 84.694

5. Approaches to automated protein crystal harvesting.

Authors: Marc C Deller; Bernhard Rupp
Journal: Acta Crystallogr F Struct Biol Commun Date: 2014-01-28 Impact factor: 1.056

6. High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

Authors: Jana Broecker; Takefumi Morizumi; Wei-Lin Ou; Viviane Klingel; Anling Kuo; David J Kissick; Andrii Ishchenko; Ming-Yue Lee; Shenglan Xu; Oleg Makarov; Vadim Cherezov; Craig M Ogata; Oliver P Ernst
Journal: Nat Protoc Date: 2018-01-04 Impact factor: 13.491

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.

Review 1. Automated robotic harvesting of protein crystals-addressing a critical bottleneck or instrumentation overkill?

2. First experiences with semi-autonomous robotic harvesting of protein crystals.

3. Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course.

Review 4. Cryo-EM in drug discovery: achievements, limitations and prospects.

5. Approaches to automated protein crystal harvesting.

6. High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

7. Crystal structure of rhodocytin, a ligand for the platelet-activating receptor CLEC-2.

8. A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF.

Review 9. Fragment-based screening by protein crystallography: successes and pitfalls.

10. The use of workflows in the design and implementation of complex experiments in macromolecular crystallography.