Literature DB >> 16967202

Sclerosing polidocanol injections in mid-portion Achilles tendinosis: remaining good clinical results and decreased tendon thickness at 2-year follow-up.

Bengt Lind1, Lars Ohberg, Håkan Alfredson.   

Abstract

The short-term results after treatment with sclerosing polidocanol injections have been shown to be good in patients with chronic painful mid-portion Achilles tendinosis. This study aimed to evaluate the longer-term effects on tendon thickness, structure and vascularity, patient satisfaction with treatment, and pain during tendon loading activity. Ultrasonography (US) + colour Doppler (CD) was used for evaluation of the tendon, and the patients graded the amount of pain during tendon loading activity on a VAS. Forty-two patient's tendons (23 men and 19 women, mean age 53 years) with a long duration (mean 32 months) of pain symptoms from mid-portion Achilles tendinosis (US + CD showed a localised thickening, structural changes and neovascularisation), were at three (mean) occasions (6-8 weeks in between) treated with US and CD guided injections of the sclerosing substance polidocanol, targeting the area with neovessels ventral to the tendon. After treatment, 37 patients were satisfied with the results of the treatment and back to previous (before injury) activity level. At the 2-year follow-up (mean 23 months), 38 patients were satisfied with the results of the treatment, and there was a significant reduction in VAS (from 75 to 7; P < 0.05). US showed a significant reduction in the mean mid-portion tendon thickness (from 10 to 8 mm, P < 0.05) and a "more normal" structure. CD showed no, or a few, remaining neovessels in the majority of the successfully treated tendons. In conclusion, treatment with sclerosing polidocanol injections in patients with chronic painful mid-portion Achilles tendinosis showed remaining good clinical results at a 2-year follow-up. Decreased tendon thickness and improved structure after treatment, might indicate a remodelling potential?

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16967202     DOI: 10.1007/s00167-006-0161-3

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  16 in total

1.  Ultrasound and Power Doppler findings in jumper's knee - preliminary observations.

Authors:  L Terslev; E Qvistgaard; S Torp-Pedersen; J Laetgaard; B Danneskiold-Samsøe; H Bliddal
Journal:  Eur J Ultrasound       Date:  2001-07

2.  Vascular NK-1 receptor occurrence in normal and chronic painful Achilles and patellar tendons: studies on chemically unfixed as well as fixed specimens.

Authors:  Sture Forsgren; Patrik Danielson; Håkan Alfredson
Journal:  Regul Pept       Date:  2005-03-30

3.  Sclerosing injections to areas of neo-vascularisation reduce pain in chronic Achilles tendinopathy: a double-blind randomised controlled trial.

Authors:  Håkan Alfredson; Lars Ohberg
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2005-02-02       Impact factor: 4.342

Review 4.  Achilles tendon injuries in athletes.

Authors:  M Kvist
Journal:  Sports Med       Date:  1994-09       Impact factor: 11.136

5.  Indications for the sclerosing agent polidocanol (aetoxisclerol dexo, aethoxisklerol kreussler)

Authors:  J J Guex
Journal:  J Dermatol Surg Oncol       Date:  1993-10

6.  Ultrasound guided sclerosis of neovessels in painful chronic Achilles tendinosis: pilot study of a new treatment.

Authors:  Lars Ohberg; H Alfredson
Journal:  Br J Sports Med       Date:  2002-06       Impact factor: 13.800

7.  Eccentric training in patients with chronic Achilles tendinosis: normalised tendon structure and decreased thickness at follow up.

Authors:  L Ohberg; R Lorentzon; H Alfredson
Journal:  Br J Sports Med       Date:  2004-02       Impact factor: 13.800

8.  The Australian polidocanol (aethoxysklerol) study. Results at 2 years.

Authors:  P Conrad; G M Malouf; M C Stacey
Journal:  Dermatol Surg       Date:  1995-04       Impact factor: 3.398

9.  Ultrasonography in the differential diagnosis of Achilles tendon injuries and related disorders. A comparison between pre-operative ultrasonography and surgical findings.

Authors:  M Paavola; T Paakkala; P Kannus; M Järvinen
Journal:  Acta Radiol       Date:  1998-11       Impact factor: 1.990

10.  Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis? An investigation using ultrasonography and colour Doppler, immunohistochemistry, and diagnostic injections.

Authors:  Håkan Alfredson; Lars Ohberg; Sture Forsgren
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2003-08-09       Impact factor: 4.342

View more
  37 in total

Review 1.  Treatment of midportion Achilles tendinopathy: an evidence-based overview.

Authors:  Ruben Zwiers; Johannes I Wiegerinck; C Niek van Dijk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-11-01       Impact factor: 4.342

Review 2.  Ultrasound-guided treatments for chronic Achilles tendinopathy: an update and current status.

Authors:  Nevin T Wijesekera; Ne Siang Chew; Justin C Lee; Adam W Mitchell; James D Calder; Jeremiah C Healy
Journal:  Skeletal Radiol       Date:  2010-02-01       Impact factor: 2.199

3.  Topical polidocanol application in combination with static stretching in tendinopathies: a prospective pilot study.

Authors:  Matthias Gatz; Simone Schrading; Timm Dirrichs; Marcel Betsch; Markus Tingart; Björn Rath; Christiane Kuhl; Valentin Quack
Journal:  Muscles Ligaments Tendons J       Date:  2017-05-10

Review 4.  Radiological interventions for soft tissue injuries in sport.

Authors:  R S D Campbell; A J Dunn
Journal:  Br J Radiol       Date:  2012-05-02       Impact factor: 3.039

5.  Neovascularization in Achilles tendinopathy: have we been chasing a red herring?

Authors:  Johannes L Tol; Filippo Spiezia; Nicola Maffulli
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-08-14       Impact factor: 4.342

6.  Ultrasound-guided dry needling with percutaneous paratenon decompression for chronic Achilles tendinopathy.

Authors:  Andrea Yeo; Namita Kendall; Sunderarajan Jayaraman
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-12-02       Impact factor: 4.342

7.  Treatment of midportion Achilles tendinosis: similar clinical results with US and CD-guided surgery outside the tendon and sclerosing polidocanol injections.

Authors:  Håkan Alfredson; Lars Ohberg; Ewa Zeisig; Ronny Lorentzon
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2007-09-18       Impact factor: 4.342

Review 8.  Pathogenesis of tendinopathies: inflammation or degeneration?

Authors:  Michele Abate; Karin Gravare Silbernagel; Carl Siljeholm; Angelo Di Iorio; Daniele De Amicis; Vincenzo Salini; Suzanne Werner; Roberto Paganelli
Journal:  Arthritis Res Ther       Date:  2009-06-30       Impact factor: 5.156

9.  Endoscopic treatment of chronic mid-portion Achilles tendinopathy: novel technique with short-term results.

Authors:  Hajo Thermann; Ioannis S Benetos; Christina Panelli; Iosif Gavriilidis; Sven Feil
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2009-03-14       Impact factor: 4.342

Review 10.  Interventional musculoskeletal US: an update on materials and methods.

Authors:  Guido Robotti; Maria Grazia Canepa; Chandra Bortolotto; Ferdinando Draghi
Journal:  J Ultrasound       Date:  2013-04-30
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.