Literature DB >> 17879083

Treatment of midportion Achilles tendinosis: similar clinical results with US and CD-guided surgery outside the tendon and sclerosing polidocanol injections.

Håkan Alfredson1, Lars Ohberg, Ewa Zeisig, Ronny Lorentzon.   

Abstract

Sclerosing polidocanol injections targeting the area with vasculo/neural ingrowth on the ventral side of the tendon have previously been demonstrated to give good clinical results in patients with chronic painful midportion Achilles tendinosis. In this study, 20 consecutive patients (9 men and 11 women, mean age 46 years) with chronic painful midportion Achilles tendinosis were treated with either sclerosing polidocanol injections (Group A) or open surgical revision of the area with vasculo/neural ingrowth on the ventral side of the Achilles tendon (Group B). Before treatment, all patients had structural tendon changes and increased blood flow-neovascularisation demonstrated with US and colour Doppler. Under US and colour Doppler-guidance, both the injections and the surgical revision targeted the area with neovessels just outside the ventral part of the tendon. A maximum of two sclerosing injection treatments, with 6-8 weeks in-between, were given. For evaluation, the patients recorded the severity of Achilles tendon pain during tendon loading activity (their recreational or sport activity), before and after treatment, on a VAS. Patient global satisfaction with treatment was also assessed. At the 3 months follow-up 6/9 (one patient was excluded) patients in Group A, and 8/10 patients in Group B, were satisfied with the treatment and had a significantly reduced level of tendon pain (Group A VAS from 76 to 24, P < 0.05, Group B VAS from 75 to 21, P < 0.05). There was one deep infection in Group B. At the 6 months follow-up, 6/9 patients in Group A, and 10/10 patients in Group B were satisfied. In summary, both treatment with sclerosing polidocanol injections and open surgical revision outside the ventral Achilles midportion show promising short-term clinical results.

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Year:  2007        PMID: 17879083     DOI: 10.1007/s00167-007-0415-8

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  14 in total

1.  Chronic Achilles tendinosis: recommendations for treatment and prevention.

Authors:  H Alfredson; R Lorentzon
Journal:  Sports Med       Date:  2000-02       Impact factor: 11.136

2.  Increased intratendinous vascularity in the early period after sclerosing injection treatment in Achilles tendinosis : a healing response?

Authors:  Håkan Alfredson; Lars Ohberg
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-03-15       Impact factor: 4.342

3.  Sclerosing polidocanol injections in mid-portion Achilles tendinosis: remaining good clinical results and decreased tendon thickness at 2-year follow-up.

Authors:  Bengt Lind; Lars Ohberg; Håkan Alfredson
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-09-12       Impact factor: 4.342

4.  Sclerosing injections to areas of neo-vascularisation reduce pain in chronic Achilles tendinopathy: a double-blind randomised controlled trial.

Authors:  Håkan Alfredson; Lars Ohberg
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2005-02-02       Impact factor: 4.342

5.  Achilles tendinosis and calf muscle strength. The effect of short-term immobilization after surgical treatment.

Authors:  H Alfredson; T Pietilä; L Ohberg; R Lorentzon
Journal:  Am J Sports Med       Date:  1998 Mar-Apr       Impact factor: 6.202

Review 6.  Achilles tendon injuries in athletes.

Authors:  M Kvist
Journal:  Sports Med       Date:  1994-09       Impact factor: 11.136

7.  Indications for the sclerosing agent polidocanol (aetoxisclerol dexo, aethoxisklerol kreussler)

Authors:  J J Guex
Journal:  J Dermatol Surg Oncol       Date:  1993-10

8.  Ultrasound guided sclerosis of neovessels in painful chronic Achilles tendinosis: pilot study of a new treatment.

Authors:  Lars Ohberg; H Alfredson
Journal:  Br J Sports Med       Date:  2002-06       Impact factor: 13.800

9.  The Australian polidocanol (aethoxysklerol) study. Results at 2 years.

Authors:  P Conrad; G M Malouf; M C Stacey
Journal:  Dermatol Surg       Date:  1995-04       Impact factor: 3.398

10.  Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis? An investigation using ultrasonography and colour Doppler, immunohistochemistry, and diagnostic injections.

Authors:  Håkan Alfredson; Lars Ohberg; Sture Forsgren
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2003-08-09       Impact factor: 4.342

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  18 in total

Review 1.  Treatment of midportion Achilles tendinopathy: an evidence-based overview.

Authors:  Ruben Zwiers; Johannes I Wiegerinck; C Niek van Dijk
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-11-01       Impact factor: 4.342

2.  Analysing the outcome of surgery for chronic Achilles tendinopathy over the last 50 years.

Authors:  Wasim S Khan; Seema Malvankar; Jagmeet S Bhamra; Ioannis Pengas
Journal:  World J Orthop       Date:  2015-07-18

3.  Endoscopic treatment of chronic mid-portion Achilles tendinopathy: novel technique with short-term results.

Authors:  Hajo Thermann; Ioannis S Benetos; Christina Panelli; Iosif Gavriilidis; Sven Feil
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2009-03-14       Impact factor: 4.342

4.  Clinical commentary of the evolution of the treatment for chronic painful mid-portion Achilles tendinopathy.

Authors:  Håkan Alfredson
Journal:  Braz J Phys Ther       Date:  2015-10-06       Impact factor: 3.377

5.  Sclerosing injections in midportion Achilles tendinopathy: a retrospective study of 25 patients.

Authors:  Martin Clementson; Ingemar Lorén; Leif Dahlberg; Mats Aström
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2008-06-13       Impact factor: 4.342

6.  Outcomes of prolotherapy for intra-tendinous Achilles tears: a case series.

Authors:  Otto Chan; Ben Havard; Sarah Morton; Mel Pritchard; Nicola Maffulli; Tom Crisp; Nat Padhiar; Jeremy David Perry; John King; Dylan Morrissey
Journal:  Muscles Ligaments Tendons J       Date:  2017-05-10

7.  Protease-activated receptors in the Achilles tendon-a potential explanation for the excessive pain signalling in tendinopathy.

Authors:  Jens Christensen; Håkan Alfredson; Gustav Andersson
Journal:  Mol Pain       Date:  2015-03-17       Impact factor: 3.395

Review 8.  New options in the management of tendinopathy.

Authors:  Nicola Maffulli; Umile Giuseppe Longo; Mattia Loppini; Filippo Spiezia; Vincenzo Denaro
Journal:  Open Access J Sports Med       Date:  2010-03-31

9.  Alpha-2 adrenergic stimulation triggers Achilles tenocyte hypercellularity: Comparison between two model systems.

Authors:  L J Backman; G Andersson; G Fong; H Alfredson; A Scott; P Danielson
Journal:  Scand J Med Sci Sports       Date:  2012-01-31       Impact factor: 4.221

Review 10.  Surgical treatment for achilles tendinopathy - a systematic review.

Authors:  Heinz Lohrer; Sina David; Tanja Nauck
Journal:  BMC Musculoskelet Disord       Date:  2016-05-10       Impact factor: 2.362

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