Literature DB >> 16883779

Fluostatins C-E, novel members of the fluostatin family produced by Streptomyces strain Acta 1383.

Stefanie Baur1, Jörg Niehaus, Amalia D Karagouni, Efstathios A Katsifas, Kalliopi Chalkou, Christos Meintanis, Amanda L Jones, Michael Goodfellow, Alan C Ward, Winfried Beil, Kathrin Schneider, Roderich D Süssmuth, Hans-Peter Fiedler.   

Abstract

Three new members of the fluostatin family, fluostatins C-E, were discovered in a culture filtrate extract of strain Acta 1383 during an HPLC screening program. The producing strain belongs to the genus Streptomyces and is closely related to type strains classified in the Streptomyces lavendulae 16S rRNA subclade. Fluostatins are named by their characteristic fluorenone chromophore. Fluostatin C shows moderate activity against selected human tumor cell lines.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16883779     DOI： 10.1038/ja.2006.41

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  10 in total

1.  Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries.

Authors:  Kenji L Kurita; Emerson Glassey; Roger G Linington
Journal:  Proc Natl Acad Sci U S A       Date:  2015-09-14       Impact factor: 11.205

2.  Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the α/β-fold epoxide hydrolase Alp1U.

Authors:  Liping Zhang; Bidhan Chandra De; Wenjun Zhang; Attila Mándi; Zhuangjie Fang; Chunfang Yang; Yiguang Zhu; Tibor Kurtán; Changsheng Zhang
Journal:  J Biol Chem       Date:  2020-10-01       Impact factor: 5.157

3.  Iodine-mediated synthesis of benzo[a]fluorenones from yne-enones.

Authors:  Sikkandarkani Akbar; V John Tamilarasan; Kannupal Srinivasan
Journal:  RSC Adv       Date:  2019-07-30       Impact factor: 3.361

4.  Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines.

Authors:  Chunshuai Huang; Chunfang Yang; Wenjun Zhang; Liping Zhang; Bidhan Chandra De; Yiguang Zhu; Xiaodong Jiang; Chunyan Fang; Qingbo Zhang; Cheng-Shan Yuan; Hung-Wen Liu; Changsheng Zhang
Journal:  Nat Commun       Date:  2018-05-25       Impact factor: 14.919

Review 5.  The functional differentiation of the post-PKS tailoring oxygenases contributed to the chemical diversities of atypical angucyclines.

Authors:  Keqiang Fan; Qian Zhang
Journal:  Synth Syst Biotechnol       Date:  2018-11-14

6.  Marine Bacterial Aromatic Polyketides From Host-Dependent Heterologous Expression and Fungal Mode of Cyclization.

Authors:  Chunshuai Huang; Chunfang Yang; Yiguang Zhu; Wenjun Zhang; Chengshan Yuan; Changsheng Zhang
Journal:  Front Chem       Date:  2018-10-30       Impact factor: 5.221

7.  Flavin-enabled reductive and oxidative epoxide ring opening reactions.

Authors:  Bidhan Chandra De; Wenjun Zhang; Chunfang Yang; Attila Mándi; Chunshuai Huang; Liping Zhang; Wei Liu; Mark W Ruszczycky; Yiguang Zhu; Ming Ma; Ghader Bashiri; Tibor Kurtán; Hung-Wen Liu; Changsheng Zhang
Journal:  Nat Commun       Date:  2022-08-20       Impact factor: 17.694

8.  Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation.

Authors:  Chunfang Yang; Liping Zhang; Wenjun Zhang; Chunshuai Huang; Yiguang Zhu; Xiaodong Jiang; Wei Liu; Mengran Zhao; Bidhan Chandra De; Changsheng Zhang
Journal:  Nat Commun       Date:  2022-09-14       Impact factor: 17.694

9.  Streptomyces rochei ACTA1551, an indigenous Greek isolate studied as a potential biocontrol agent against Fusarium oxysporum f.sp. lycopersici.

Authors:  Grammatiki S Kanini; Efstathios A Katsifas; Alexandros L Savvides; Amalia D Karagouni
Journal:  Biomed Res Int       Date:  2013-05-20       Impact factor: 3.411

10.  Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis.

Authors:  Yuanqi Wang; Changsheng Zhang; Yi-Lei Zhao; Rosalinda Zhao; Kendall N Houk
Journal:  Biomolecules       Date:  2020-05-26
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.