Literature DB >> 19578943

Diastereoselective synthesis of fused [1,3]oxazines from ethyl pyruvate, activated acetylenes and N-heterocycles.

Issa Yavari1, Anvar Mirzaei, Zinatosadat Hossaini, Sanaz Souri.   

Abstract

The 1:1 zwitterionic intermediates obtained from the reaction between isoquinoline, quinoline, pyridine, or N-methylimidazole with activated acetylenes are trapped by ethyl pyruvate to produce highly functionalized fused [1,3]oxazines in good yields.

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Year:  2009        PMID： 19578943     DOI： 10.1007/s11030-009-9174-4

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  15 in total

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Review 2.  "Multi-component reactions : emerging chemistry in drug discovery" 'from xylocain to crixivan'.

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3.  Stereoselective palladium-catalyzed four-component cascade synthesis of pyrrolidinyl-, pyrazolidinyl-, and isoxazolidinyl isoquinolines.

Authors:  H Ali Dondas; Colin W G Fishwick; Xinjie Gai; Ronald Grigg; Colin Kilner; Nuethip Dumrongchai; Boonsong Kongkathip; Ngampong Kongkathip; Chatchwan Polysuk; Visuvanathar Sridharan
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4.  A direct, one step synthesis of imidazoles from imines and acid chlorides: a palladium catalyzed multicomponent coupling approach.

Authors:  Ali R Siamaki; Bruce A Arndtsen
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Review 5.  Cascade reactions in total synthesis.

Authors:  K C Nicolaou; David J Edmonds; Paul G Bulger
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6.  Three-component synthesis of functionalized 5-oxo-4,5-dihydroindeno[1,2-b]pyrans.

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Journal:  Mol Divers       Date:  2006-06-16       Impact factor: 2.943

7.  Modulating the reactivity of alpha-isocyanoacetates: multicomponent synthesis of 5-methoxyoxazoles and furopyrrolones.

Authors:  Damien Bonne; Mouloud Dekhane; Jieping Zhu
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

8.  Palladium-catalyzed sequential alkylation-alkenylation reactions: new three-component coupling leading to oxacycles.

Authors:  Sandrine Pache; Mark Lautens
Journal:  Org Lett       Date:  2003-12-11       Impact factor: 6.005

Review 9.  The direct catalytic asymmetric mannich reaction.

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Journal:  Acc Chem Res       Date:  2004-02       Impact factor: 22.384

10.  Reaction between alkyl isocyanides and isopropylidene Meldrum's acid in the presence of bidentate nucleophiles.

Authors:  Issa Yavari; Maryam Sabbaghan; Zinatossadat Hossaini
Journal:  Mol Divers       Date:  2006-11-23       Impact factor: 3.364
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  2 in total

1.  Synthesis of sterically congested 1,3,4-oxadiazole derivatives from aromatic carboxylic acids, N,N-dicyclohexylcarbodiimide and (N-isocyanimino)triphenylphosphorane.

Authors:  Fatemeh Zeinali Nasrabadi; Ali Ramazani; Yavar Ahmadi
Journal:  Mol Divers       Date:  2011-03-20       Impact factor: 2.943

2.  Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins.

Authors:  Li-Juan Zhang; Chao-Guo Yan
Journal:  Mol Divers       Date:  2014-08-19       Impact factor: 2.943
  2 in total

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