Literature DB >> 1663920

Detection of human antibody against the human papillomavirus type 16 E7 protein.

M Hashido1, T Kanda, S Zanma, S Watanabe, N Komiyama, H Yoshikawa, N Yamaguchi, T Kawana, K Yoshiike.   

Abstract

We examined 500 human sera for the presence of antibody against the human papillomavirus type 16 E7 protein by enzyme-linked immunosorbent assay with bacterially expressed fusion protein lac-E7, and by radioimmunoprecipitation and immunofluorescence assays with the E7 protein expressed in monkey COS-1 cells. The anti-E7 antibody was detectable in 6 out of 54 cases of cervical carcinoma, but in none of the others, including patients with other gynecologic cancers, those with sexually transmitted diseases, and healthy adults. The data indicate that expression of the E7 protein is closely related to cervical carcinoma.

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Year:  1991        PMID： 1663920      PMCID： PMC5918352          DOI： 10.1111/j.1349-7006.1991.tb01813.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  32 in total

1.  Human papillomavirus type 16 E7 protein expressed in Escherichia coli and monkey COS-1 cells: immunofluorescence detection of the nuclear E7 protein.

Authors:  H Sato; S Watanabe; A Furuno; K Yoshiike
Journal:  Virology       Date:  1989-05       Impact factor: 3.616

2.  The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.

Authors:  K Münger; W C Phelps; V Bubb; P M Howley; R Schlegel
Journal:  J Virol       Date:  1989-10       Impact factor: 5.103

3.  The major human papillomavirus protein in cervical cancers is a cytoplasmic phosphoprotein.

Authors:  D Smotkin; F O Wettstein
Journal:  J Virol       Date:  1987-05       Impact factor: 5.103

4.  Transforming activity of human papillomavirus type 16 DNA sequence in a cervical cancer.

Authors:  Y Tsunokawa; N Takebe; T Kasamatsu; M Terada; T Sugimura
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

5.  Expression of human papillomavirus type 16 E7 gene induces DNA synthesis of rat 3Y1 cells.

Authors:  H Sato; A Furuno; K Yoshiike
Journal:  Virology       Date:  1989-01       Impact factor: 3.616

6.  Antibodies against the human papillomavirus type 16 early proteins in human sera: correlation of anti-E7 reactivity with cervical cancer.

Authors:  I Jochmus-Kudielka; A Schneider; R Braun; R Kimmig; U Koldovsky; K E Schneweis; K Seedorf; L Gissmann
Journal:  J Natl Cancer Inst       Date:  1989-11-15       Impact factor: 13.506

7.  The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A.

Authors:  W C Phelps; C L Yee; K Münger; P M Howley
Journal:  Cell       Date:  1988-05-20       Impact factor: 41.582

8.  Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA.

Authors:  M Dürst; R T Dzarlieva-Petrusevska; P Boukamp; N E Fusenig; L Gissmann
Journal:  Oncogene       Date:  1987       Impact factor: 9.867

9.  Papillomavirus genomes in human cervical tumors: analysis of their transcriptional activity.

Authors:  H Lehn; P Krieg; G Sauer
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

10.  Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells.

Authors:  G Matlashewski; J Schneider; L Banks; N Jones; A Murray; L Crawford
Journal:  EMBO J       Date:  1987-06       Impact factor: 11.598
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