| Literature DB >> 16582424 |
Arnold B Barton1, David B Kaback.
Abstract
The endmost chromosome I ORF is silenced by a natural telomere position effect. YAR073W/IMD1 was found to be transcribed at much higher levels in sir3 mutants and when its adjacent telomere was removed from it. These results suggest that telomeres play a role in silencing actual genes.Entities:
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Year: 2006 PMID: 16582424 PMCID: PMC1526490 DOI: 10.1534/genetics.106.058420
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562