| Literature DB >> 15893722 |
Vincenzo Pirrotta1, David S Gross.
Abstract
Transcriptional silencing in budding yeast and fruit fly is mediated by fundamentally unrelated proteins that assemble very different chromatin structures. Surprisingly, the repressive mechanisms evolved from these very different materials have similar features, including an epigenetic mode of inheritance and a block to transcription based on interference with the assembly or function of the promoter complex rather than with the binding of gene-specific activators.Entities:
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Year: 2005 PMID: 15893722 DOI: 10.1016/j.molcel.2005.04.013
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970