| Literature DB >> 16541368 |
L M Jacola1, M B Schapiro, V J Schmithorst, A W Byars, R H Strawsburg, J P Szaflarski, E Plante, S K Holland.
Abstract
We used verb generation and story listening tasks during fMRI to study language organization in children (7, 9 and 12 years old) with perinatal left MCA infarctions. Healthy, age-matched comparison children (n = 39) showed activation in left Broca's area during the verb generation task; in contrast, stroke subjects showed activation either bilaterally or in the right hemisphere homologue during both tasks. In Wernicke's area, comparison subjects showed left lateralization (verb generation) and bilateral activation (L > R) (story listening). Stroke subjects instead showed bilateral or right lateralization (verb generation) and bilateral activation (R > L) (story listening). Language is distributed atypically in children with perinatal left hemisphere stroke.Entities:
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Year: 2006 PMID： 16541368 PMCID： PMC1859843 DOI： 10.1055/s-2006-923934
Source DB: PubMed Journal: Neuropediatrics ISSN： 0174-304X Impact factor: 1.947