Literature DB >> 16531545

Germline epimutations of APC are not associated with inherited colorectal polyposis.

M Hitchins, C Suter, J Wong, K Cheong, N Hawkins, B Leggett, R Scott, A Spigelman, I Tomlinson, D Martin, R Ward.   

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Year:  2006        PMID： 16531545      PMCID： PMC1856153          DOI： 10.1136/gut.2005.087486

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


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  10 in total

1.  Small changes in expression affect predisposition to tumorigenesis.

Authors:  Hai Yan; Zuzana Dobbie; Stephen B Gruber; Sanford Markowitz; Kathy Romans; Francis M Giardiello; Kenneth W Kinzler; Bert Vogelstein
Journal:  Nat Genet       Date:  2001-12-17       Impact factor: 38.330

2.  Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.

Authors:  Nada Al-Tassan; Nikolas H Chmiel; Julie Maynard; Nick Fleming; Alison L Livingston; Geraint T Williams; Angela K Hodges; D Rhodri Davies; Sheila S David; Julian R Sampson; Jeremy P Cheadle
Journal:  Nat Genet       Date:  2002-01-30       Impact factor: 38.330

3.  Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.

Authors:  M Esteller; A Sparks; M Toyota; M Sanchez-Cespedes; G Capella; M A Peinado; S Gonzalez; G Tarafa; D Sidransky; S J Meltzer; S B Baylin; J G Herman
Journal:  Cancer Res       Date:  2000-08-15       Impact factor: 12.701

4.  A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor.

Authors:  Isabella Gazzoli; Massimo Loda; Judy Garber; Sapna Syngal; Richard D Kolodner
Journal:  Cancer Res       Date:  2002-07-15       Impact factor: 12.701

5.  Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis.

Authors:  Jie Chen; Christoph Röcken; Cathy Lofton-Day; Hans-Ulrich Schulz; Oliver Müller; Nadine Kutzner; Peter Malfertheiner; Matthias P A Ebert
Journal:  Carcinogenesis       Date:  2004-09-16       Impact factor: 4.944

6.  Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability.

Authors:  Yasuyuki Miyakura; Kokichi Sugano; Takayuki Akasu; Teruhiko Yoshida; Masato Maekawa; Soh Saitoh; Hideyuki Sasaki; Tadashi Nomizu; Fumio Konishi; Shin Fujita; Yoshihiro Moriya; Hideo Nagai
Journal:  Clin Gastroenterol Hepatol       Date:  2004-02       Impact factor: 11.382

7.  APC gene: database of germline and somatic mutations in human tumors and cell lines.

Authors:  C Béroud; T Soussi
Journal:  Nucleic Acids Res       Date:  1996-01-01       Impact factor: 16.971

8.  Germline epimutation of MLH1 in individuals with multiple cancers.

Authors:  Catherine M Suter; David I K Martin; Robyn L Ward
Journal:  Nat Genet       Date:  2004-04-04       Impact factor: 38.330

9.  MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.

Authors:  Megan Hitchins; Rachel Williams; Kayfong Cheong; Nimita Halani; Vita A P Lin; Deborah Packham; Sue Ku; Andrew Buckle; Nicholas Hawkins; John Burn; Steven Gallinger; Jack Goldblatt; Judy Kirk; Ian Tomlinson; Rodney Scott; Allan Spigelman; Catherine Suter; David Martin; Graeme Suthers; Robyn Ward
Journal:  Gastroenterology       Date:  2005-11       Impact factor: 22.682

10.  A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.

Authors:  Guro E Lind; Lin Thorstensen; Tone Løvig; Gunn I Meling; Richard Hamelin; Torleiv O Rognum; Manel Esteller; Ragnhild A Lothe
Journal:  Mol Cancer       Date:  2004-10-11       Impact factor: 27.401
  10 in total
  5 in total

Review 1.  Constitutional epimutation as a mechanism for cancer causality and heritability?

Authors:  Megan P Hitchins
Journal:  Nat Rev Cancer       Date:  2015-09-18       Impact factor: 60.716

Review 2.  Colorectal cancer: a model for epigenetic tumorigenesis.

Authors:  J J L Wong; N J Hawkins; R L Ward
Journal:  Gut       Date:  2006-07-13       Impact factor: 23.059

3.  Hsp90 affecting chromatin remodeling might explain transgenerational epigenetic inheritance in Drosophila.

Authors:  Douglas M Ruden; Xiangyi Lu
Journal:  Curr Genomics       Date:  2008-11       Impact factor: 2.236

4.  Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients.

Authors:  Hidetaka Yamada; Kazuya Shinmura; Masanori Goto; Moriya Iwaizumi; Hiroyuki Konno; Hideki Kataoka; Masami Yamada; Takachika Ozawa; Toshihiro Tsuneyoshi; Fumihiko Tanioka; Haruhiko Sugimura
Journal:  Mol Cancer       Date:  2009-08-12       Impact factor: 27.401

5.  Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia.

Authors:  Justin J-L Wong; Katherine A Lau; Natalia Pinello; John E J Rasko
Journal:  Cancer Sci       Date:  2014-10-18       Impact factor: 6.716
  5 in total

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