Literature DB >> 8594558

APC gene: database of germline and somatic mutations in human tumors and cell lines.

C Béroud1, T Soussi.   

Abstract

A database is described in which over 700 mutations in the human APC gene of tumors (colon cancer predominantly) are compiled from the literature. It includes both molecular informations about the mutations and also clinical data about the patients. A software have been designed in order to analyse all these informations in the database.

Entities:  

Mesh：

Year:  1996        PMID： 8594558      PMCID： PMC145597          DOI： 10.1093/nar/24.1.121

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  8 in total

Review 1.  The role of the adenomatous polyposis coli (APC) gene in human cancers.

Authors:  Y Nakamura
Journal:  Adv Cancer Res       Date:  1993       Impact factor: 6.242

2.  Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients.

Authors:  S Olschwang; A Tiret; P Laurent-Puig; M Muleris; R Parc; G Thomas
Journal:  Cell       Date:  1993-12-03       Impact factor: 41.582

3.  Alleles of the APC gene: an attenuated form of familial polyposis.

Authors:  L Spirio; S Olschwang; J Groden; M Robertson; W Samowitz; G Joslyn; L Gelbert; A Thliveris; M Carlson; B Otterud
Journal:  Cell       Date:  1993-12-03       Impact factor: 41.582

4.  Association between wild type and mutant APC gene products.

Authors:  L K Su; K A Johnson; K J Smith; D E Hill; B Vogelstein; K W Kinzler
Journal:  Cancer Res       Date:  1993-06-15       Impact factor: 12.701

5.  Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

Authors:  H Nagase; Y Miyoshi; A Horii; T Aoki; M Ogawa; J Utsunomiya; S Baba; T Sasazuki; Y Nakamura
Journal:  Cancer Res       Date:  1992-07-15       Impact factor: 12.701

Review 6.  Mutations of the APC (adenomatous polyposis coli) gene.

Authors:  H Nagase; Y Nakamura
Journal:  Hum Mutat       Date:  1993       Impact factor: 4.878

Review 7.  Mutations in the APC gene and their implications for protein structure and function.

Authors:  P Polakis
Journal:  Curr Opin Genet Dev       Date:  1995-02       Impact factor: 5.578

8.  Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

Authors:  K Ory; Y Legros; C Auguin; T Soussi
Journal:  EMBO J       Date:  1994-08-01       Impact factor: 11.598
  8 in total
  70 in total

Review 1.  [Carcinogenesis and hereditart colon cancers].

Authors:  F Kullmann
Journal:  Internist (Berl)       Date:  2003-03       Impact factor: 0.743

2.  A Rare Case of FAP in Kashmir Valley.

Authors:  A Syed Sameer; Arshad A Pandith; Nidda Syeed; Mushtaq A Siddiqi; Nissar A Chowdri
Journal:  Indian J Surg       Date:  2011-02-02       Impact factor: 0.656

3.  Genotype-phenotype correlations in attenuated adenomatous polyposis coli.

Authors:  C Soravia; T Berk; L Madlensky; A Mitri; H Cheng; S Gallinger; Z Cohen; B Bapat
Journal:  Am J Hum Genet       Date:  1998-06       Impact factor: 11.025

4.  Hepatoblastoma and APC gene mutation in familial adenomatous polyposis.

Authors:  F M Giardiello; G M Petersen; J D Brensinger; M C Luce; M C Cayouette; J Bacon; S V Booker; S R Hamilton
Journal:  Gut       Date:  1996-12       Impact factor: 23.059

5.  Software and database for the analysis of mutations in the human LDL receptor gene.

Authors:  M Varret; J P Rabès; G Collod-Béroud; C Junien; C Boileau; C Béroud
Journal:  Nucleic Acids Res       Date:  1997-01-01       Impact factor: 16.971

6.  The GDB Human Genome Database Anno 1997.

Authors:  K H Fasman; S I Letovsky; P Li; R W Cottingham; D T Kingsbury
Journal:  Nucleic Acids Res       Date:  1997-01-01       Impact factor: 16.971

7.  Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma.

Authors:  Jae-Hyuk Lee; Susan C Abraham; Hyun-Soo Kim; Jong-Hee Nam; Chan Choi; Min-Cheol Lee; Chang-Soo Park; Sang-Woo Juhng; Asif Rashid; Stanley R Hamilton; Tsung-Teh Wu
Journal:  Am J Pathol       Date:  2002-08       Impact factor: 4.307

8.  The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.

Authors:  I M Frayling; N E Beck; M Ilyas; I Dove-Edwin; P Goodman; K Pack; J A Bell; C B Williams; S V Hodgson; H J Thomas; I C Talbot; W F Bodmer; I P Tomlinson
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

9.  Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes.

Authors:  Z J Wang; F Taylor; M Churchman; G Norbury; I Tomlinson
Journal:  Am J Pathol       Date:  1998-08       Impact factor: 4.307

10.  Germline epimutations of APC are not associated with inherited colorectal polyposis.

Authors:  M Hitchins; C Suter; J Wong; K Cheong; N Hawkins; B Leggett; R Scott; A Spigelman; I Tomlinson; D Martin; R Ward
Journal:  Gut       Date:  2006-04       Impact factor: 23.059
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