Literature DB >> 11743581

Small changes in expression affect predisposition to tumorigenesis.

Hai Yan1, Zuzana Dobbie, Stephen B Gruber, Sanford Markowitz, Kathy Romans, Francis M Giardiello, Kenneth W Kinzler, Bert Vogelstein.   

Abstract

We have used quantitative measures of gene expression to show that constitutional 50% decreases in expression of one adenomatous polyposis coli tumor suppressor gene (APC) allele can lead to the development of familial adenomatous polyposis.

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Year:  2001        PMID： 11743581     DOI： 10.1038/ng799

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  77 in total

1.  Expression profiling with oligonucleotide arrays: technologies and applications for neurobiology.

Authors:  Timothy J Sendera; David Dorris; Ramesh Ramakrishnan; Allen Nguyen; Dionisios Trakas; Abhijit Mazumder
Journal:  Neurochem Res       Date:  2002-10       Impact factor: 3.996

2.  Digital genotyping and haplotyping with polymerase colonies.

Authors:  Robi D Mitra; Vincent L Butty; Jay Shendure; Benjamin R Williams; David E Housman; George M Church
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-02       Impact factor: 11.205

3.  Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations.

Authors:  Devin Dressman; Hai Yan; Giovanni Traverso; Kenneth W Kinzler; Bert Vogelstein
Journal:  Proc Natl Acad Sci U S A       Date:  2003-07-11       Impact factor: 11.205

4.  Allelic variation in gene expression is common in the human genome.

Authors:  H Shuen Lo; Zhining Wang; Ying Hu; Howard H Yang; Sheryl Gere; Kenneth H Buetow; Maxwell P Lee
Journal:  Genome Res       Date:  2003-08       Impact factor: 9.043

5.  Gene-expression variation within and among human populations.

Authors:  John D Storey; Jennifer Madeoy; Jeanna L Strout; Mark Wurfel; James Ronald; Joshua M Akey
Journal:  Am J Hum Genet       Date:  2007-01-11       Impact factor: 11.025

6.  Accurate quantitation of allele-specific expression patterns by analysis of DNA melting.

Authors:  Sangkyun Jeong; Yoonsoo Hahn; Qi Rong; Karl Pfeifer
Journal:  Genome Res       Date:  2007-06-01       Impact factor: 9.043

7.  Detection of allelic imbalance in the gene expression of hMSH2 or RB1 in lymphocytes from pedigrees of hereditary, nonpolyposis, colorectal cancer and retinoblastoma by an RNA difference plot.

Authors:  Yoshinori Murakami; Kana Isogai; Hiroyuki Tomita; Mika Sakurai-Yageta; Tomoko Maruyama; Akio Hidaka; Kiyoshi Nose; Kokichi Sugano; Akihiro Kaneko
Journal:  J Hum Genet       Date:  2004-10-08       Impact factor: 3.172

8.  RADIOSENSITIVITY TO HIGH ENERGY IRON IONS IS INFLUENCED BY HETEROZYGOSITY for ATM, RAD9 and BRCA1.

Authors:  G Zhou; L B Smilenov; H B Lieberman; T Ludwig; E J Hall
Journal:  Adv Space Res       Date:  2010-09-01       Impact factor: 2.152

9.  Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer.

Authors:  Hugo Pinheiro; Renata Bordeira-Carriço; Susana Seixas; Joana Carvalho; Janine Senz; Patrícia Oliveira; Patrícia Inácio; Leonor Gusmão; Jorge Rocha; David Huntsman; Raquel Seruca; Carla Oliveira
Journal:  Hum Mol Genet       Date:  2009-12-04       Impact factor: 6.150

10.  Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes.

Authors:  Joanne Ngeow; Xin He; Jessica L Mester; Junying Lei; Todd Romigh; Mohammed S Orloff; Mira Milas; Charis Eng
Journal:  J Clin Endocrinol Metab       Date:  2012-10-12       Impact factor: 5.958
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