Literature DB >> 16524828

Finding the molecular basis of complex genetic variation in humans and mice.

Richard Mott1.   

Abstract

I survey the state of the art in complex trait analysis, including the use of new experimental and computational technologies and resources becoming available, and the challenges facing us. I also discuss how the prospects of rodent model systems compare with association mapping in humans.

Entities:  

Mesh：

Year:  2006        PMID： 16524828      PMCID： PMC1609339          DOI： 10.1098/rstb.2005.1798

Source DB:  PubMed          Journal:  Philos Trans R Soc Lond B Biol Sci        ISSN： 0962-8436            Impact factor:   6.237


  65 in total

Review 1.  The nature and identification of quantitative trait loci: a community's view.

Authors:  Oduola Abiola; Joe M Angel; Philip Avner; Alexander A Bachmanov; John K Belknap; Beth Bennett; Elizabeth P Blankenhorn; David A Blizard; Valerie Bolivar; Gundrun A Brockmann; Kari J Buck; Jean-Francoise Bureau; William L Casley; Elissa J Chesler; James M Cheverud; Gary A Churchill; Melloni Cook; John C Crabbe; Wim E Crusio; Ariel Darvasi; Gerald de Haan; Peter Dermant; R W Doerge; Rosemary W Elliot; Charles R Farber; Lorraine Flaherty; Jonathan Flint; Howard Gershenfeld; John P Gibson; Jing Gu; Weikuan Gu; Heinz Himmelbauer; Robert Hitzemann; Hui-Chen Hsu; Kent Hunter; Fuad F Iraqi; Ritsert C Jansen; Thomas E Johnson; Byron C Jones; Gerd Kempermann; Frank Lammert; Lu Lu; Kenneth F Manly; Douglas B Matthews; Juan F Medrano; Margarete Mehrabian; Guy Mittlemann; Beverly A Mock; Jeffrey S Mogil; Xavier Montagutelli; Grant Morahan; John D Mountz; Hiroki Nagase; Richard S Nowakowski; Bruce F O'Hara; Alexander V Osadchuk; Beverly Paigen; Abraham A Palmer; Jeremy L Peirce; Daniel Pomp; Michael Rosemann; Glenn D Rosen; Leonard C Schalkwyk; Ze'ev Seltzer; Stephen Settle; Kazuhiro Shimomura; Siming Shou; James M Sikela; Linda D Siracusa; Jimmy L Spearow; Cory Teuscher; David W Threadgill; Linda A Toth; Ayo A Toye; Csaba Vadasz; Gary Van Zant; Edward Wakeland; Robert W Williams; Huang-Ge Zhang; Fei Zou
Journal:  Nat Rev Genet       Date:  2003-11       Impact factor: 53.242

2.  Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping.

Authors:  John K Belknap
Journal:  Mamm Genome       Date:  2003-11       Impact factor: 2.957

3.  Mpdz is a quantitative trait gene for drug withdrawal seizures.

Authors:  Renee L Shirley; Nicole A R Walter; Matthew T Reilly; Christoph Fehr; Kari J Buck
Journal:  Nat Neurosci       Date:  2004-06-20       Impact factor: 24.884

4.  Little epistasis for anxiety-related measures in the DeFries strains of laboratory mice.

Authors:  Jonathan Flint; John C DeFries; Norman D Henderson
Journal:  Mamm Genome       Date:  2004-02       Impact factor: 2.957

Review 5.  Genome-wide association studies for common diseases and complex traits.

Authors:  Joel N Hirschhorn; Mark J Daly
Journal:  Nat Rev Genet       Date:  2005-02       Impact factor: 53.242

6.  An integrative genomics approach to infer causal associations between gene expression and disease.

Authors:  Eric E Schadt; John Lamb; Xia Yang; Jun Zhu; Steve Edwards; Debraj Guhathakurta; Solveig K Sieberts; Stephanie Monks; Marc Reitman; Chunsheng Zhang; Pek Yee Lum; Amy Leonardson; Rolf Thieringer; Joseph M Metzger; Liming Yang; John Castle; Haoyuan Zhu; Shera F Kash; Thomas A Drake; Alan Sachs; Aldons J Lusis
Journal:  Nat Genet       Date:  2005-06-19       Impact factor: 38.330

7.  Multiple blood pressure QTL on rat Chromosome 2 defined by congenic Dahl rats.

Authors:  Michael R Garrett; John P Rapp
Journal:  Mamm Genome       Date:  2002-01       Impact factor: 2.957

8.  Reciprocal rat chromosome 2 congenic strains reveal contrasting blood pressure and heart rate QTL.

Authors:  Adamu Alemayehu; Laura Breen; Drahomira Krenova; Morton P Printz
Journal:  Physiol Genomics       Date:  2002-09-03       Impact factor: 3.107

9.  Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness.

Authors:  Paul Van Eerdewegh; Randall D Little; Josée Dupuis; Richard G Del Mastro; Kathy Falls; Jason Simon; Dana Torrey; Sunil Pandit; Joyce McKenny; Karen Braunschweiger; Alison Walsh; Ziying Liu; Brooke Hayward; Colleen Folz; Susan P Manning; Alicia Bawa; Lisa Saracino; Michelle Thackston; Youssef Benchekroun; Neva Capparell; Mei Wang; Ron Adair; Yun Feng; JoAnn Dubois; Michael G FitzGerald; Hui Huang; René Gibson; Kristina M Allen; Alex Pedan; Melvyn R Danzig; Shelby P Umland; Robert W Egan; Francis M Cuss; Steuart Rorke; Joanne B Clough; John W Holloway; Stephen T Holgate; Tim P Keith
Journal:  Nature       Date:  2002-07-10       Impact factor: 49.962

10.  Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse.

Authors:  Mathew T Pletcher; Philip McClurg; Serge Batalov; Andrew I Su; S Whitney Barnes; Erica Lagler; Ron Korstanje; Xiaosong Wang; Deborah Nusskern; Molly A Bogue; Richard J Mural; Beverly Paigen; Tim Wiltshire
Journal:  PLoS Biol       Date:  2004-11-09       Impact factor: 8.029
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  7 in total

1.  Introduction. Bioinformatics: from molecules to systems.

Authors:  David T Jones; Michael J E Sternberg; Janet M Thornton
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-03-29       Impact factor: 6.237

Review 2.  Genome and proteome annotation: organization, interpretation and integration.

Authors:  Gabrielle A Reeves; David Talavera; Janet M Thornton
Journal:  J R Soc Interface       Date:  2009-02-06       Impact factor: 4.118

3.  An integrated in silico gene mapping strategy in inbred mice.

Authors:  Alessandra C L Cervino; Ariel Darvasi; Mohammad Fallahi; Christopher C Mader; Nicholas F Tsinoremas
Journal:  Genetics       Date:  2006-10-08       Impact factor: 4.562

Review 4.  Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation.

Authors:  Aarnoud C van der Spoel; Richard Mott; Frances M Platt
Journal:  Pharmacogenomics       Date:  2008-06       Impact factor: 2.533

5.  Performance of genomic selection in mice.

Authors:  Andrés Legarra; Christèle Robert-Granié; Eduardo Manfredi; Jean-Michel Elsen
Journal:  Genetics       Date:  2008-08-30       Impact factor: 4.562

6.  Effect of genotype imputation on genome-enabled prediction of complex traits: an empirical study with mice data.

Authors:  Vivian P S Felipe; Hayrettin Okut; Daniel Gianola; Martinho A Silva; Guilherme J M Rosa
Journal:  BMC Genet       Date:  2014-12-29       Impact factor: 2.797

7.  Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans.

Authors:  Maria De Luca; Michelle Moses Chambers; Krista Casazza; Kerry H Lok; Gary R Hunter; Barbara A Gower; José R Fernández
Journal:  BMC Genet       Date:  2008-08-11       Impact factor: 2.797
  7 in total

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