Literature DB >> 16387873

Positive selection can create false hotspots of recombination.

Floyd A Reed1, Sarah A Tishkoff.   

Abstract

Simulations of positive directional selection, under parameter values appropriate for approximating human genetic diversity and rates of recombination, reveal that the effects of strong selective sweeps on patterns of linkage disequilibrium (LD) mimic the pattern expected with recombinant hotspots.

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Mesh：

Year:  2005        PMID： 16387873      PMCID： PMC1456281          DOI： 10.1534/genetics.105.052183

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  41 in total

1.  Detecting a local signature of genetic hitchhiking along a recombining chromosome.

Authors:  Yuseob Kim; Wolfgang Stephan
Journal:  Genetics       Date:  2002-02       Impact factor: 4.562

2.  The signature of positive selection at randomly chosen loci.

Authors:  Molly Przeworski
Journal:  Genetics       Date:  2002-03       Impact factor: 4.562

Review 3.  Towards a molecular characterization of adaptation in local populations.

Authors:  Christian Schlötterer
Journal:  Curr Opin Genet Dev       Date:  2002-12       Impact factor: 5.578

4.  A neutral explanation for the correlation of diversity with recombination rates in humans.

Authors:  Ines Hellmann; Ingo Ebersberger; Susan E Ptak; Svante Pääbo; Molly Przeworski
Journal:  Am J Hum Genet       Date:  2003-05-08       Impact factor: 11.025

Review 5.  Hot and cold spots of recombination in the human genome: the reason we should find them and how this can be achieved.

Authors:  Norman Arnheim; Peter Calabrese; Magnus Nordborg
Journal:  Am J Hum Genet       Date:  2003-05-22       Impact factor: 11.025

Review 6.  Estimating recombination rates from population-genetic data.

Authors:  Michael P H Stumpf; Gilean A T McVean
Journal:  Nat Rev Genet       Date:  2003-12       Impact factor: 53.242

Review 7.  Signatures of natural selection in the human genome.

Authors:  Michael Bamshad; Stephen P Wooding
Journal:  Nat Rev Genet       Date:  2003-02       Impact factor: 53.242

Review 8.  Distribution of meiotic recombination sites.

Authors:  Bernard de Massy
Journal:  Trends Genet       Date:  2003-09       Impact factor: 11.639

9.  The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae.

Authors:  Alison J Rattray; Brenda K Shafer; Carolyn B McGill; Jeffrey N Strathern
Journal:  Genetics       Date:  2002-11       Impact factor: 4.562

Review 10.  Haplotype blocks and linkage disequilibrium in the human genome.

Authors:  Jeffrey D Wall; Jonathan K Pritchard
Journal:  Nat Rev Genet       Date:  2003-08       Impact factor: 53.242
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  31 in total

1.  Genetic and evolutionary correlates of fine-scale recombination rate variation in Drosophila persimilis.

Authors:  Laurie S Stevison; Mohamed A F Noor
Journal:  J Mol Evol       Date:  2010-10-02       Impact factor: 2.395

2.  Fine-scale crossover rate heterogeneity in Drosophila pseudoobscura.

Authors:  Elizabeth T Cirulli; Richard M Kliman; Mohamed A F Noor
Journal:  J Mol Evol       Date:  2006-12-06       Impact factor: 2.395

3.  The structure of linkage disequilibrium around a selective sweep.

Authors:  Gil McVean
Journal:  Genetics       Date:  2006-12-28       Impact factor: 4.562

4.  Power and precision of alternate methods for linkage disequilibrium mapping of quantitative trait loci.

Authors:  H H Zhao; R L Fernando; J C M Dekkers
Journal:  Genetics       Date:  2007-02-04       Impact factor: 4.562

5.  Approximating genealogies for partially linked neutral loci under a selective sweep.

Authors:  P Pfaffelhuber; A Studeny
Journal:  J Math Biol       Date:  2007-03-30       Impact factor: 2.259

6.  Linkage disequilibrium under genetic hitchhiking in finite populations.

Authors:  P Pfaffelhuber; A Lehnert; W Stephan
Journal:  Genetics       Date:  2008-05       Impact factor: 4.562

Review 7.  Recombination rate variation in closely related species.

Authors:  C S Smukowski; M A F Noor
Journal:  Heredity (Edinb)       Date:  2011-06-15       Impact factor: 3.821

8.  A fast estimate for the population recombination rate based on regression.

Authors:  Kao Lin; Andreas Futschik; Haipeng Li
Journal:  Genetics       Date:  2013-04-15       Impact factor: 4.562

9.  Genetic crossovers are predicted accurately by the computed human recombination map.

Authors:  Pavel P Khil; R Daniel Camerini-Otero
Journal:  PLoS Genet       Date:  2010-01-29       Impact factor: 5.917

10.  Human population differentiation is strongly correlated with local recombination rate.

Authors:  Alon Keinan; David Reich
Journal:  PLoS Genet       Date:  2010-03-26       Impact factor: 5.917
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