Literature DB >> 16378565

Factors identifying higher risk rectal bleeding in general practice.

Brian G Ellis1, Michael R Thompson.   

Abstract

BACKGROUND: Rectal bleeding is a common symptom. The ability to distinguish those patients having serious underlying pathology from those with self-limiting conditions is a continuing dilemma in general practice. AIM: To determine the factors affecting the predictive and diagnostic value of rectal bleeding for bowel cancer in primary care. DESIGN OF STUDY: One-year prospective observational study.
SETTING: Three large general practices.
METHOD: Three hundred and nineteen consecutive patients over the age of 34 years consulting their GPs with rectal bleeding were included in the study. Investigation was by flexible sigmoidoscopy or a questionnaire and review of all patients took place after 18 months. The main outcome measures were consultation rates; the prevalence of cancer, colitis and significant polyps in patients presenting with rectal bleeding; its diagnostic value when occurring with or without a change in bowel habit, perianal symptoms and abdominal pain.
RESULTS: The consultation rate for rectal bleeding in patients over the age of 34 years was 15 per 1000 per year; 3.4% had colorectal cancer. The prevalence of cancer increased to 9.2% when the rectal bleeding was associated with a change in bowel habit, and to 11.1% when it was without perianal symptoms. Thirty-six per cent of cancer patients had a palpable rectal mass.
CONCLUSION: Over 96% of the patients who present to their GPs with rectal bleeding do not have cancer. Greater awareness of the diagnostic value of the different symptom combinations of rectal bleeding could help GPs adopt different management strategies for patients at higher and very low risk of cancer.

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Mesh:

Year:  2005        PMID: 16378565      PMCID: PMC1570526     

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN: 0960-1643            Impact factor:   5.386


  15 in total

1.  Rectal bleeding and colorectal cancer in general practice: diagnostic study.

Authors:  H Wauters; V Van Casteren; F Buntinx
Journal:  BMJ       Date:  2000-10-21

2.  Rectal bleeding: prevalence and consultation behaviour.

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Journal:  BMJ       Date:  1995-08-19

3.  Incidence and causes of rectal bleeding in general practice as detected by colonoscopy.

Authors:  J V Metcalf; J Smith; R Jones; C O Record
Journal:  Br J Gen Pract       Date:  1996-03       Impact factor: 5.386

4.  Rectal bleeding. Do other symptoms aid in diagnosis?

Authors:  A Mant; E L Bokey; P H Chapuis; M Killingback; W Hughes; S G Koorey; I Cook; K J Goulston; O F Dent
Journal:  Dis Colon Rectum       Date:  1989-03       Impact factor: 4.585

5.  Self-reported rectal bleeding in a United States community: prevalence, risk factors, and health care seeking.

Authors:  N J Talley; M Jones
Journal:  Am J Gastroenterol       Date:  1998-11       Impact factor: 10.864

6.  Prevention of colorectal cancer by once-only sigmoidoscopy.

Authors:  W S Atkin; J Cuzick; J M Northover; D K Whynes
Journal:  Lancet       Date:  1993-03-20       Impact factor: 79.321

7.  Value of a risk questionnaire in screening for colorectal neoplasm.

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Journal:  Br J Surg       Date:  1989-03       Impact factor: 6.939

8.  Predictive value of signs and symptoms for colorectal cancer in patients with rectal bleeding in general practice.

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Journal:  Fam Pract       Date:  1995-09       Impact factor: 2.267

Review 9.  Occurrence and clinical significance of overt blood loss per rectum in the general population and in medical practice.

Authors:  G H Fijten; G H Blijham; J A Knottnerus
Journal:  Br J Gen Pract       Date:  1994-07       Impact factor: 5.386

10.  Colorectal cancer and polyps in patients aged 40 years and over who consult a GP with rectal bleeding.

Authors:  N Nørrelund; H Nørrelund
Journal:  Fam Pract       Date:  1996-04       Impact factor: 2.267

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  23 in total

1.  Colorectal cancer in primary care.

Authors:  David Weller
Journal:  BMJ       Date:  2006-07-08

2.  Colorectal cancer and rectal bleeding in primary care: urban or rural myth?

Authors:  Sanjay Purkayastha; Ara Darzi
Journal:  BMJ       Date:  2006-07-22

3.  Colorectal cancer risk.

Authors:  Nader Al-Hassan
Journal:  Br J Gen Pract       Date:  2006-07       Impact factor: 5.386

4.  Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study.

Authors:  Jennifer du Toit; William Hamilton; Kevin Barraclough
Journal:  BMJ       Date:  2006-06-21

Review 5.  Systematic review of clinical features of suspected colorectal cancer in primary care.

Authors:  M Elisabeth Del Giudice; Emily T Vella; Amanda Hey; Marko Simunovic; William Harris; Cheryl Levitt
Journal:  Can Fam Physician       Date:  2014-08       Impact factor: 3.275

Review 6.  The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review.

Authors:  Margaret Astin; Tom Griffin; Richard D Neal; Peter Rose; William Hamilton
Journal:  Br J Gen Pract       Date:  2011-05       Impact factor: 5.386

Review 7.  Hematochezia in the young patient: a review of health-seeking behavior, physician attitudes, and controversies in management.

Authors:  Rashid Khan; David Hyman
Journal:  Dig Dis Sci       Date:  2009-02-24       Impact factor: 3.199

Review 8.  Value of symptoms and additional diagnostic tests for colorectal cancer in primary care: systematic review and meta-analysis.

Authors:  Petra Jellema; Daniëlle A W M van der Windt; David J Bruinvels; Christian D Mallen; Stijn J B van Weyenberg; Chris J Mulder; Henrica C W de Vet
Journal:  BMJ       Date:  2010-03-31

9.  Alarm symptoms in early diagnosis of cancer in primary care: cohort study using General Practice Research Database.

Authors:  Roger Jones; Radoslav Latinovic; Judith Charlton; Martin C Gulliford
Journal:  BMJ       Date:  2007-05-10

Review 10.  Diagnostic accuracy systematic review of rectal bleeding in combination with other symptoms, signs and tests in relation to colorectal cancer.

Authors:  M Olde Bekkink; C McCowan; G A Falk; C Teljeur; F A Van de Laar; T Fahey
Journal:  Br J Cancer       Date:  2009-11-24       Impact factor: 7.640

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