Literature DB >> 16790459

Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study.

Jennifer du Toit1, William Hamilton, Kevin Barraclough.   

Abstract

OBJECTIVE: To measure the risk of colorectal cancer and adenoma with new onset rectal bleeding reported to primary care.
DESIGN: Cohort study.
SETTING: A rural general practice in the United Kingdom. PARTICIPANTS: Patients aged 45 or more with new onset rectal bleeding, irrespective of other symptoms. MAIN OUTCOME MEASURES: Percentage of participants in whom colorectal cancer or colonic adenoma was identified after investigation of the bowel.
RESULTS: During a 10 year period, 265 patients reported new rectal bleeding. Of these, 15 (5.7%, 95% confidence interval 3.2% to 9.2%) had colorectal cancer, and 13 (4.9%, 2.6% to 8.4%) had colonic adenoma. Only two of the patients with cancer had had diarrhoea.
CONCLUSIONS: One in 10 patients aged 45 or more with new onset rectal bleeding had colonic neoplasia, so investigation of the bowel should be offered to all such patients, whether or not they have other symptoms.

Entities:  

Mesh:

Year:  2006        PMID: 16790459      PMCID: PMC1489264          DOI: 10.1136/bmj.38846.684850.2F

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  4 in total

1.  Rectal bleeding and colorectal cancer in general practice: diagnostic study.

Authors:  H Wauters; V Van Casteren; F Buntinx
Journal:  BMJ       Date:  2000-10-21

2.  Factors identifying higher risk rectal bleeding in general practice.

Authors:  Brian G Ellis; Michael R Thompson
Journal:  Br J Gen Pract       Date:  2005-12       Impact factor: 5.386

3.  Predictive value of signs and symptoms for colorectal cancer in patients with rectal bleeding in general practice.

Authors:  G H Fijten; R Starmans; J W Muris; H J Schouten; G H Blijham; J A Knottnerus
Journal:  Fam Pract       Date:  1995-09       Impact factor: 2.267

4.  Clinical features of colorectal cancer before diagnosis: a population-based case-control study.

Authors:  W Hamilton; A Round; D Sharp; T J Peters
Journal:  Br J Cancer       Date:  2005-08-22       Impact factor: 7.640

  4 in total
  17 in total

1.  Colorectal cancer in primary care.

Authors:  David Weller
Journal:  BMJ       Date:  2006-07-08

2.  Colorectal cancer and rectal bleeding in primary care: urban or rural myth?

Authors:  Sanjay Purkayastha; Ara Darzi
Journal:  BMJ       Date:  2006-07-22

3.  General practice by numbers: presentation to final outcome.

Authors:  Mark Shapley; Gemma Mansell; Kevin Barraclough; Peter Croft
Journal:  Br J Gen Pract       Date:  2013-04       Impact factor: 5.386

Review 4.  Systematic review of clinical features of suspected colorectal cancer in primary care.

Authors:  M Elisabeth Del Giudice; Emily T Vella; Amanda Hey; Marko Simunovic; William Harris; Cheryl Levitt
Journal:  Can Fam Physician       Date:  2014-08       Impact factor: 3.275

Review 5.  The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review.

Authors:  Margaret Astin; Tom Griffin; Richard D Neal; Peter Rose; William Hamilton
Journal:  Br J Gen Pract       Date:  2011-05       Impact factor: 5.386

Review 6.  Most bowel cancer symptoms do not indicate colorectal cancer and polyps: a systematic review.

Authors:  Barbara-Ann Adelstein; Petra Macaskill; Siew F Chan; Peter H Katelaris; Les Irwig
Journal:  BMC Gastroenterol       Date:  2011-05-30       Impact factor: 3.067

7.  Colorectal cancer and rectal bleeding in primary care: rectal bleeding needs attention in primary care.

Authors:  Christopher M Newman; Guy F Nash; Tom Armstrong; Kieren Darcy
Journal:  BMJ       Date:  2006-07-22

8.  Alarm symptoms in early diagnosis of cancer in primary care: cohort study using General Practice Research Database.

Authors:  Roger Jones; Radoslav Latinovic; Judith Charlton; Martin C Gulliford
Journal:  BMJ       Date:  2007-05-10

Review 9.  Diagnostic accuracy systematic review of rectal bleeding in combination with other symptoms, signs and tests in relation to colorectal cancer.

Authors:  M Olde Bekkink; C McCowan; G A Falk; C Teljeur; F A Van de Laar; T Fahey
Journal:  Br J Cancer       Date:  2009-11-24       Impact factor: 7.640

10.  The risk of colorectal cancer with symptoms at different ages and between the sexes: a case-control study.

Authors:  William Hamilton; Robert Lancashire; Debbie Sharp; Tim J Peters; Kk Cheng; Tom Marshall
Journal:  BMC Med       Date:  2009-04-17       Impact factor: 8.775

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.