Literature DB >> 16357125

A blueprint for a Human Epigenome Project: the AACR Human Epigenome Workshop.

Peter A Jones1, Robert Martienssen.   

Abstract

Epigenetic processes control the packaging and function of the human genome and contribute to normal and pathologic states, including cancer. The time is ripe to undertake an international effort to identify all the chemical changes and relationships between chromatin constituents that provide function to the genetic code. A timely workshop of leading experts, convened by the American Association for Cancer Research (AACR), confirmed that the technology is at hand to begin defining human epigenomes at high resolution.

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Year:  2005        PMID: 16357125     DOI: 10.1158/0008-5472.CAN-05-3865

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  35 in total

Review 1.  Methods in DNA methylation profiling.

Authors:  Tao Zuo; Benjamin Tycko; Ta-Ming Liu; Juey-Jen L Lin; Tim H-M Huang
Journal:  Epigenomics       Date:  2009-12       Impact factor: 4.778

2.  Tackling the epigenome: challenges and opportunities for collaboration.

Authors:  John S Satterlee; Dirk Schübeler; Huck-Hui Ng
Journal:  Nat Biotechnol       Date:  2010-10       Impact factor: 54.908

3.  Taking the measure of the methylome.

Authors:  Stephan Beck
Journal:  Nat Biotechnol       Date:  2010-10       Impact factor: 54.908

Review 4.  Epigenetics and human disease: translating basic biology into clinical applications.

Authors:  David Rodenhiser; Mellissa Mann
Journal:  CMAJ       Date:  2006-01-31       Impact factor: 8.262

Review 5.  Applying whole-genome studies of epigenetic regulation to study human disease.

Authors:  J D Lieb; S Beck; M L Bulyk; P Farnham; N Hattori; S Henikoff; X S Liu; K Okumura; K Shiota; T Ushijima; J M Greally
Journal:  Cytogenet Genome Res       Date:  2006       Impact factor: 1.636

6.  Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes.

Authors:  Feng Miao; Xiwei Wu; Lingxiao Zhang; Arthur D Riggs; Rama Natarajan
Journal:  J Immunol       Date:  2008-02-15       Impact factor: 5.422

7.  Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia.

Authors:  Lynda B Bennett; Kristen H Taylor; Gerald L Arthur; Farahnaz B Rahmatpanah; Sam I Hooshmand; Charles W Caldwell
Journal:  Epigenomics       Date:  2010-02-01       Impact factor: 4.778

8.  Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data.

Authors:  Zailong Wang; Pearlly Yan; Dustin Potter; Charis Eng; Tim H-M Huang; Shili Lin
Journal:  BMC Bioinformatics       Date:  2007-02-01       Impact factor: 3.169

9.  Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth.

Authors:  Chibo Hong; K Scott Moorefield; Peter Jun; Kenneth D Aldape; Samir Kharbanda; Heidi S Phillips; Joseph F Costello
Journal:  Proc Natl Acad Sci U S A       Date:  2007-06-19       Impact factor: 11.205

10.  Systems biology of embryogenesis.

Authors:  Lucas B Edelman; Sriram Chandrasekaran; Nathan D Price
Journal:  Reprod Fertil Dev       Date:  2010       Impact factor: 2.311

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