| Literature DB >> 16325403 |
Isabel C F R Ferreira1, Maria-João R P Queiroz, Miguel Vilas-Boas, Letícia M Estevinho, Agathe Begouin, Gilbert Kirsch.
Abstract
The antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure-activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO(2)Et, CO(2)H).Entities:
Mesh：
Substances：
Year: 2005 PMID： 16325403 DOI： 10.1016/j.bmcl.2005.11.035
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823