Literature DB >> 16317550

Meta-analysis of randomized clinical trials comparing drainage alone vs primary sphincter-cutting procedures for anorectal abscess-fistula.

H M Quah1, C L Tang, K W Eu, S Y E Chan, M Samuel.   

Abstract

BACKGROUND AND AIM: Concurrent definitive treatment of underlying fistulas from infected anal glands at the time when the anorectal abscesses are drained is controversial as this is associated with a higher incidence of faecal incontinence, failure and recurrence. This meta-analysis was conducted to determine the merits of drainage alone vs primary sphincter-cutting procedures (which includes fistulotomy and fistulectomy) for anorectal abscess-fistula.
METHODS: Medline, Embase and Cochrane Central Register of Controlled Trials database searches identified all randomized controlled trials using the keywords: anorectal abscess, anal sepsis, drainage, fistulotomy, fistulectomy or surgery from 1966 to 2004. The outcome variables analysed were recurrence, faecal continence and wound-healing times.
RESULTS: Five trials were considered suitable for the meta-analysis, with a total of 405 patients. Sphincter-cutting procedures for anorectal abscesses resulted in 83% reduction in recurrence rate [relative risk (RR) 0.17, 95% confidence interval (CI) 0.09-0.32, p<0.001]. However, there was a tendency to a higher risk of faecal incontinence to flatus and soiling when primary sphincter-cutting procedure was performed (RR 2.46, 95% CI 0.75-8.06, p=0.140).
CONCLUSION: There is no conclusive evidence if simple drainage or sphincter-cutting procedure is better in the treatment of anorectal abscess-fistula.

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Mesh:

Year:  2005        PMID: 16317550     DOI: 10.1007/s00384-005-0060-y

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


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  21 in total

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Review 3.  Complex anal fistula remains a challenge for colorectal surgeon.

Authors:  F Cadeddu; F Salis; G Lisi; I Ciangola; G Milito
Journal:  Int J Colorectal Dis       Date:  2015-01-09       Impact factor: 2.571

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Authors:  A Amato; C Bottini; P De Nardi; P Giamundo; A Lauretta; A Realis Luc; V Piloni
Journal:  Tech Coloproctol       Date:  2020-01-23       Impact factor: 3.781

8.  Porcine dermal collagen matrix injection may enhance flap repair surgery for complex anal fistula.

Authors:  Pierpaolo Sileri; Luana Franceschilli; Giovanna Del Vecchio Blanco; Vito M Stolfi; Giulio P Angelucci; Achille L Gaspari
Journal:  Int J Colorectal Dis       Date:  2010-10-17       Impact factor: 2.571

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Authors:  Shahram Paydar; Ahmad Izadpanah; Leila Ghahramani; Seyed Vahid Hosseini; Alimohammad Bananzadeh; Salar Rahimikazerooni; Faranak Bahrami
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Journal:  Int J Colorectal Dis       Date:  2013-05-01       Impact factor: 2.571

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