Literature DB >> 25566951

Complex anal fistula remains a challenge for colorectal surgeon.

F Cadeddu1, F Salis, G Lisi, I Ciangola, G Milito.   

Abstract

AIM: Anal fistula is a common proctological problem to both patient and physician throughout surgical history. Several surgical and sphincter-sparing approaches have been described for the management of fistula-in-ano, aimed to minimize the recurrence and to preserve the continence. We aimed to systematically review the available studies relating to the surgical management of anal fistulas.
MATERIAL AND METHODS: A Medline search was performed using the PubMed, Ovid, Embase, and Cochrane databases to identify articles reporting on fistula-in-ano management, aimed to find out the current techniques available, the new technologies, and their effectiveness in order to delineate a gold standard treatment algorithm.
RESULTS: The management of low anal fistulas is usually straightforward, given that fistulotomy is quite effective, and if the fistula has been properly evaluated, continence disturbance is minimal. On the contrary, high complex fistulas are challenging, because cure and continence are directly competing priorities.
CONCLUSIONS: Conventional fistula surgery techniques have their place, but new technologies such as fibrin glues, dermal collagen injection, the anal fistula plugs, and stem cell injection offer alternative approaches whose long-term efficacy needs to be further clarified in large long-term randomized trials.

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Year:  2015        PMID: 25566951     DOI: 10.1007/s00384-014-2104-7

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  66 in total

Review 1.  Fibrin glue in the management of anal fistulae.

Authors:  T M Hammond; M F Grahn; P J Lunniss
Journal:  Colorectal Dis       Date:  2004-09       Impact factor: 3.788

Review 2.  Fistula-in-ano: advances in treatment.

Authors:  Samer Deeba; Omer Aziz; Parvinder S Sains; Ara Darzi
Journal:  Am J Surg       Date:  2008-05-07       Impact factor: 2.565

3.  Repair of fistulas-in-ano using autologous fibrin tissue adhesive.

Authors:  J R Cintron; J J Park; C P Orsay; R K Pearl; R L Nelson; H Abcarian
Journal:  Dis Colon Rectum       Date:  1999-05       Impact factor: 4.585

4.  Randomized clinical trial of local gentamicin-collagen treatment in advancement flap repair for anal fistula.

Authors:  U-M Gustafsson; W Graf
Journal:  Br J Surg       Date:  2006-10       Impact factor: 6.939

5.  Fibrin glue-antibiotic mixture in the treatment of anal fistulae: experience with 69 cases.

Authors:  L Patrlj; B Kocman; M Martinac; S Jadrijevic; T Sosa; B Sebecic; B Brkljacic
Journal:  Dig Surg       Date:  2000       Impact factor: 2.588

6.  Radiosurgical fistulotomy; an alternative to conventional procedure in fistula in ano.

Authors:  Pravin J Gupta
Journal:  Curr Surg       Date:  2003 Sep-Oct

7.  Required length of follow-up after transanal advancement flap repair of high transsphincteric fistulas.

Authors:  L E Mitalas; M P Gosselink; D M J Oom; D D E Zimmerman; W R Schouten
Journal:  Colorectal Dis       Date:  2009-09       Impact factor: 3.788

8.  Randomized clinical trial comparing simple drainage of anorectal abscess with and without fistula track treatment.

Authors:  I Oliver; F J Lacueva; F Pérez Vicente; A Arroyo; R Ferrer; P Cansado; F Candela; R Calpena
Journal:  Int J Colorectal Dis       Date:  2002-08-21       Impact factor: 2.571

9.  Radiofrequency fistulectomy vs. diathermic fistulotomy for submucosal fistulas: a randomized trial.

Authors:  V Filingeri; G Gravante; E Baldessari; C U Casciani
Journal:  Eur Rev Med Pharmacol Sci       Date:  2004 May-Jun       Impact factor: 3.507

10.  Functional outcome after transperineal rectocele repair with porcine dermal collagen implant.

Authors:  Neil J Smart; Mark A Mercer-Jones
Journal:  Dis Colon Rectum       Date:  2007-09       Impact factor: 4.585

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  8 in total

1.  The clinical efficacy of stem cell therapy for complex perianal fistulas: a meta-analysis.

Authors:  S Choi; B G Jeon; G Chae; S-J Lee
Journal:  Tech Coloproctol       Date:  2019-05-02       Impact factor: 3.781

2.  Effective and long-term outcome following ligation of the intersphincteric fistula tract (LIFT) for transsphincteric fistula.

Authors:  Hong-Jin Chen; Gui-Dong Sun; Ping Zhu; Zai-Long Zhou; Yu-Gen Chen; Bo-Lin Yang
Journal:  Int J Colorectal Dis       Date:  2016-11-23       Impact factor: 2.571

3.  Advancement Flap for Treatment of Complex Cryptoglandular Anal Fistula: Prediction of Therapy Success or Failure Using Anamnestic and Clinical Parameters.

Authors:  Lars Boenicke; Eduard Karsten; Hubert Zirngibl; Peter Ambe
Journal:  World J Surg       Date:  2017-09       Impact factor: 3.352

Review 4.  Comprehensive literature review of the applications of surgical laser in benign anal conditions.

Authors:  Ahmed Hossam Elfallal; Mohammad Fathy; Samy Abbas Elbaz; Sameh Hany Emile
Journal:  Lasers Med Sci       Date:  2022-05-23       Impact factor: 2.555

5.  Autologous adipose tissue-derived stem cells for the treatment of complex perianal fistulas not associated with Crohn's disease: a phase II clinical trial for safety and efficacy.

Authors:  S Choi; S-B Ryoo; K J Park; D-S Kim; K-H Song; K H Kim; S S Chung; E J Shin; Y B Cho; S T Oh; W-K Kang; M H Kim
Journal:  Tech Coloproctol       Date:  2017-05-31       Impact factor: 3.781

6.  Efficacy and Safety of Sphincter-Preserving Surgery in the Treatment of Complex Anal Fistula: A Network Meta-Analysis.

Authors:  Hua Huang; Lijiang Ji; Yunfei Gu; Youran Li; Shanshan Xu
Journal:  Front Surg       Date:  2022-02-08

7.  Human Amniotic Membrane for the Treatment of Cryptoglandular Anal Fistulas.

Authors:  Carlo Ratto; Ornella Parolini; Angelo Alessandro Marra; Valentina Orticelli; Angelo Parello; Paola Campennì; Veronica De Simone; Diletta Trojan; Francesco Litta
Journal:  J Clin Med       Date:  2022-03-01       Impact factor: 4.241

8.  Autologous adipose-derived stem cells for the treatment of Crohn's fistula-in-ano: an open-label, controlled trial.

Authors:  Chungen Zhou; Meng Li; Yang Zhang; Min Ni; Yehuang Wang; Dachao Xu; Yang Shi; Bo Zhang; Yanni Chen; Yan Huang; Sumin Zhang; Hongzhen Shi; Bin Jiang
Journal:  Stem Cell Res Ther       Date:  2020-03-17       Impact factor: 6.832

  8 in total

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