Literature DB >> 20953873

Porcine dermal collagen matrix injection may enhance flap repair surgery for complex anal fistula.

Pierpaolo Sileri1, Luana Franceschilli, Giovanna Del Vecchio Blanco, Vito M Stolfi, Giulio P Angelucci, Achille L Gaspari.   

Abstract

INTRODUCTION: The use of biomaterials to treat anal fistula has drawn great interest. More recently, a porcine dermal matrix injection has been proposed as infill biomaterial to treat fistulas.
METHODS: We propose a novel approach consisting in non-cutting seton positioning followed by flap repair associated with dermal matrix injection into the fistula tracts after several weeks.
RESULTS: We report our experience with this two-staged procedure on 11 consecutive patients with recurrent high trans-sphincteric fistulas with a minimum follow-up of 6 months.
CONCLUSIONS: In our experience, this two-stage approach seems to be safe and effective.

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Year:  2010        PMID: 20953873     DOI: 10.1007/s00384-010-1066-7

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  20 in total

Review 1.  Fibrin glue in the management of anal fistulae.

Authors:  T M Hammond; M F Grahn; P J Lunniss
Journal:  Colorectal Dis       Date:  2004-09       Impact factor: 3.788

Review 2.  Emerging treatments for complex perianal fistula in Crohn's disease.

Authors:  Carlos Taxonera; David A Schwartz; Damián García-Olmo
Journal:  World J Gastroenterol       Date:  2009-09-14       Impact factor: 5.742

3.  Seton treatment of high anal fistulae.

Authors:  J G Williams; C A MacLeod; D A Rothenberger; S M Goldberg
Journal:  Br J Surg       Date:  1991-10       Impact factor: 6.939

4.  Flap advancement and core fistulectomy for complex rectal fistula.

Authors:  G V Miller; P J Finan
Journal:  Br J Surg       Date:  1998-01       Impact factor: 6.939

5.  Fibrin glue as an adjunct to flap repair of anal fistulas: a randomized, controlled study.

Authors:  C Neal Ellis; Stephen Clark
Journal:  Dis Colon Rectum       Date:  2006-11       Impact factor: 4.585

6.  Treatment of fistulas-in-ano with fibrin sealant in combination with intra-adhesive antibiotics and/or surgical closure of the internal fistula opening.

Authors:  Marc Singer; José Cintron; Richard Nelson; Charles Orsay; Amir Bastawrous; Russell Pearl; Julia Sone; Herand Abcarian
Journal:  Dis Colon Rectum       Date:  2005-04       Impact factor: 4.585

7.  Anal fistula surgery. Factors associated with recurrence and incontinence.

Authors:  J Garcia-Aguilar; C Belmonte; W D Wong; S M Goldberg; R D Madoff
Journal:  Dis Colon Rectum       Date:  1996-07       Impact factor: 4.585

Review 8.  Meta-analysis of randomized clinical trials comparing drainage alone vs primary sphincter-cutting procedures for anorectal abscess-fistula.

Authors:  H M Quah; C L Tang; K W Eu; S Y E Chan; M Samuel
Journal:  Int J Colorectal Dis       Date:  2005-11-30       Impact factor: 2.571

9.  Efficacy of fibrin sealant in the management of complex anal fistula: a prospective trial.

Authors:  Gordon N Buchanan; Clive I Bartram; Robin K S Phillips; Stuart W T Gould; Steve Halligan; Tim A Rockall; Paul Sibbons; Richard G Cohen
Journal:  Dis Colon Rectum       Date:  2003-09       Impact factor: 4.585

10.  An experimentally successful new sphincter-conserving treatment for anal fistula.

Authors:  Rebecca C Himpson; C Richard G Cohen; Paul Sibbons; Robin K S Phillips
Journal:  Dis Colon Rectum       Date:  2009-04       Impact factor: 4.585

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  4 in total

1.  Ligation of the intersphincteric fistula tract (LIFT) to treat anal fistula: early results from a prospective observational study.

Authors:  P Sileri; L Franceschilli; G P Angelucci; S D'Ugo; G Milito; F Cadeddu; I Selvaggio; S Lazzaro; A L Gaspari
Journal:  Tech Coloproctol       Date:  2011-11-11       Impact factor: 3.781

Review 2.  Evaluation and management of perianal abscess and anal fistula: a consensus statement developed by the Italian Society of Colorectal Surgery (SICCR).

Authors:  A Amato; C Bottini; P De Nardi; P Giamundo; A Lauretta; A Realis Luc; G Tegon; R J Nicholls
Journal:  Tech Coloproctol       Date:  2015-09-16       Impact factor: 3.781

3.  Evaluation and management of perianal abscess and anal fistula: SICCR position statement.

Authors:  A Amato; C Bottini; P De Nardi; P Giamundo; A Lauretta; A Realis Luc; V Piloni
Journal:  Tech Coloproctol       Date:  2020-01-23       Impact factor: 3.781

4.  The Effectiveness of Porcine Dermal Collagen (Permacol(®)) on Wound Healing in the Rat Model.

Authors:  Murat Kalin; Serdar Kuru; Kemal Kismet; Aziz Mutlu Barlas; Yusuf Akif Akgun; Hesna Muzeyyen Astarci; Huseyin Ustun; Ertugrul Ertas
Journal:  Indian J Surg       Date:  2013-01-27       Impact factor: 0.656

  4 in total

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