Literature DB >> 16261171

Deinococcus radiodurans - the consummate survivor.

Michael M Cox1, John R Battista.   

Abstract

Relatively little is known about the biochemical basis of the capacity of Deinococcus radiodurans to endure the genetic insult that results from exposure to ionizing radiation and can include hundreds of DNA double-strand breaks. However, recent reports indicate that this species compensates for extensive DNA damage through adaptations that allow cells to avoid the potentially detrimental effects of DNA strand breaks. It seems that D. radiodurans uses mechanisms that limit DNA degradation and that restrict the diffusion of DNA fragments that are produced following irradiation, to preserve genetic integrity. These mechanisms also increase the efficiency of the DNA-repair proteins.

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Year:  2005        PMID: 16261171     DOI: 10.1038/nrmicro1264

Source DB:  PubMed          Journal:  Nat Rev Microbiol        ISSN: 1740-1526            Impact factor:   60.633


  184 in total

1.  Expression, purification and preliminary structural analysis of the coiled-coil domain of Deinococcus radiodurans RecN.

Authors:  Simone Pellegrino; Daniele de Sanctis; Sean McSweeney; Joanna Timmins
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2012-01-26

Review 2.  Microbial colonization and controls in dryland systems.

Authors:  Stephen B Pointing; Jayne Belnap
Journal:  Nat Rev Microbiol       Date:  2012-07-09       Impact factor: 60.633

3.  RecN is a cohesin-like protein that stimulates intermolecular DNA interactions in vitro.

Authors:  Emigdio D Reyes; Praveen L Patidar; Lee A Uranga; Angelina S Bortoletto; Shelley L Lusetti
Journal:  J Biol Chem       Date:  2010-03-31       Impact factor: 5.157

4.  Microarray analysis of the hyperthermophilic archaeon Pyrococcus furiosus exposed to gamma irradiation.

Authors:  Ernest Williams; Todd M Lowe; Jeffrey Savas; Jocelyne DiRuggiero
Journal:  Extremophiles       Date:  2006-08-08       Impact factor: 2.395

5.  Multiple-stress tolerance of ionizing radiation-resistant bacterial isolates obtained from various habitats: correlation between stresses.

Authors:  Manish Shukla; Ruchi Chaturvedi; Dhruti Tamhane; Pranav Vyas; G Archana; Shree Apte; J Bandekar; Anjana Desai
Journal:  Curr Microbiol       Date:  2006-12-18       Impact factor: 2.188

6.  Ring-like nucleoids and DNA repair through error-free nonhomologous end joining in Deinococcus radiodurans.

Authors:  Abraham Minsky; Eyal Shimoni; Joseph Englander
Journal:  J Bacteriol       Date:  2006-09       Impact factor: 3.490

7.  Chromatin organization and radio resistance in the bacterium Gemmata obscuriglobus.

Authors:  Arnon Lieber; Andrew Leis; Ariel Kushmaro; Abraham Minsky; Ohad Medalia
Journal:  J Bacteriol       Date:  2008-12-12       Impact factor: 3.490

8.  Designing antioxidant peptides.

Authors:  Barbara S Berlett; Rodney L Levine
Journal:  Redox Rep       Date:  2014-01-03       Impact factor: 4.412

9.  Purification, crystallization and phase determination of the DR1998 haem b catalase from Deinococcus radiodurans.

Authors:  Patrícia T Borges; Cecília S Miranda; Sandra P Santos; João N Carita; Carlos Frazão; Célia V Romão
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2014-04-25       Impact factor: 1.056

10.  Deinococcus radiodurans PprI switches on DNA damage response and cellular survival networks after radiation damage.

Authors:  Huiming Lu; Guanjun Gao; Guangzhi Xu; Lu Fan; Longfei Yin; Binghui Shen; Yuejin Hua
Journal:  Mol Cell Proteomics       Date:  2008-10-24       Impact factor: 5.911

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