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Literature DB >> 16249957

Recommendations for a toxicological screening ERG procedure in laboratory animals.

Serge G Rosolen¹, Florence Rigaudière, Jean-François Le Gargasson, Mitchell G Brigell.

Abstract

Electroretinography, using laboratory animals, is a commonly used technique for determining the retinal toxicity of chemical agents. In this paper, guidelines for performing this test are provided. The physiologic basis for visual testing is presented with attention to inter-species differences. Technical aspects of animal recordings are reviewed, including animal preparation, stimulation, signal conditioning, recording and data analysis. Finally, suggested protocols for recording in diurnal and nocturnal species are presented.

Entities: Disease

Mesh：

Year: 2005 PMID： 16249957 DOI： 10.1007/s10633-005-7344-y

Source DB: PubMed Journal: Doc Ophthalmol ISSN： 0012-4486 Impact factor: 2.379

16 in total

Recommendations for a toxicological screening ERG procedure in laboratory animals.

1. Guidelines for clinical electroretinography in the dog.

2. Cone-dominated ERG luminance-response function: the Photopic Hill revisited.

3. Standard for clinical electroretinography (2004 update).

4. Evaluation of different recording parameters to establish a standard for flash electroretinography in rodents.

Review 5. The distribution and nature of colour vision among the mammals.

6. Temporal properties of the mouse cone electroretinogram.

7. Improved contact lens electrode for corneal ERG recordings in mice.

8. Contribution of Kir4.1 to the mouse electroretinogram.

9. Effects of telazol and nembutal on retinal responses.

1. Harmonic analysis of the cone flicker ERG of rabbit.

2. Two distinct processes are evident in rat cone flicker ERG responses at low and high temporal frequencies.

3. Effects of Sodium Lighting On Circadian Rhythms in Rats.

4. Effects of hypercapnia on the electroretinogram in sevoflurane and isoflurane anaesthetized dogs.

5. Effects of a monocarboxylate transport 1 inhibitor, AZD3965, on retinal and visual function in the rat.

6. An adaptive ERG technique to measure normal and altered dark adaptation in the mouse.

7. Functional and Structural Effects of Erythropoietin Subconjunctival Administration in Glaucomatous Animals.

8. Chitosan and Hyaluronic Acid Nanoparticles as Vehicles of Epoetin Beta for Subconjunctival Ocular Delivery.