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Literature DB >> 16246719

E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs.

Abstract

The 3' ends of almost all eukaryotic RNAs are generated by nucleolytic cleavage. Remarkably, three groups now demonstrate that similar or identical endonucleases of the metallo-beta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, and U snRNAs.

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Year: 2005 PMID： 16246719 DOI： 10.1016/j.molcel.2005.10.009

Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970

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Cited

17 in total

Review 1. Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism.

Authors: Rafal Tomecki; Andrzej Dziembowski
Journal: RNA Date: 2010-07-30 Impact factor: 4.942

Review 2. Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production.

Authors: Keita Miyoshi; Tomohiro Miyoshi; Haruhiko Siomi
Journal: Mol Genet Genomics Date: 2010-07-02 Impact factor: 3.291

3. A subset of Drosophila integrator proteins is essential for efficient U7 snRNA and spliceosomal snRNA 3'-end formation.

Authors: Nader Ezzeddine; Jiandong Chen; Bernhard Waltenspiel; Brandon Burch; Todd Albrecht; Ming Zhuo; William D Warren; William F Marzluff; Eric J Wagner
Journal: Mol Cell Biol Date: 2010-11-15 Impact factor: 4.272

4. Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.

Authors: Nova Fong; Kristopher Brannan; Benjamin Erickson; Hyunmin Kim; Michael A Cortazar; Ryan M Sheridan; Tram Nguyen; Shai Karp; David L Bentley
Journal: Mol Cell Date: 2015-10-15 Impact factor: 17.970

E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs.

Review 1. Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism.

Review 2. Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production.

3. A subset of Drosophila integrator proteins is essential for efficient U7 snRNA and spliceosomal snRNA 3'-end formation.

4. Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.

Review 5. Formation of the 3' end of histone mRNA: getting closer to the end.

Review 6. 3' end mRNA processing: molecular mechanisms and implications for health and disease.

Review 7. Signals for pre-mRNA cleavage and polyadenylation.

Review 8. A day in the life of the spliceosome.

9. Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression.

10. The scaRNA2 is produced by an independent transcription unit and its processing is directed by the encoding region.