Literature DB >> 16237237

Resolution- versus sensitivity-effective diameter in pinhole collimation: experimental verification.

S D Metzler1, R Accorsi.   

Abstract

To account for photon penetration, the formulae used to calculate the geometric resolution of a pinhole collimator use an effective diameter d(e) rather than the physical diameter of the aperture. The expressions commonly used for d(e), however, were originally derived to include penetration in sensitivity calculations. To predict the full width at half maximum (FWHM) resolution of the point-spread function (PSF) of a knife-edge pinhole collimator, we have previously proposed simple expressions for a resolution-effective diameter d(re). Unlike those for d(e), expressions for d(re) predict both a dependence on the polar angle of the source (theta) and a non-isotropic PSF. In this paper, the new theory was tested by measuring experimentally the FWHM of the PSF. Results confirm the theoretical predictions that (a) d(re) provides the best estimates of the experimental FWHM as a function of theta and of the direction in the plane of the pinhole, (b) Paix's expression for d(e) tends to overestimate the FWHM, (c) Anger's is a better approximation, but still cannot predict the dependence on theta, and (d) the FWHM decreases with decreasing theta, i.e. resolution improves for sources at the edge of the field-of-view.

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Year:  2005        PMID: 16237237     DOI: 10.1088/0031-9155/50/21/004

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  5 in total

1.  Myocardial perfusion imaging is feasible for infarct size quantification in mice using a clinical single-photon emission computed tomography system equipped with pinhole collimators.

Authors:  Tim Wollenweber; Christian Zach; Christoph Rischpler; Rebekka Fischer; Sebastian Nowak; Stephan G Nekolla; Michael Gröbner; Christopher Ubleis; Gerald Assmann; Josef Müller-Höcker; Christian La Fougére; Guido Böning; Paul Cumming; Wolfgang-Michael Franz; Marcus Hacker
Journal:  Mol Imaging Biol       Date:  2009-11-25       Impact factor: 3.488

2.  Multi-pinhole SPECT Imaging with Silicon Strip Detectors.

Authors:  Todd E Peterson; Sepideh Shokouhi; Lars R Furenlid; Donald W Wilson
Journal:  IEEE Trans Nucl Sci       Date:  2009-06-16       Impact factor: 1.679

3.  Design of a Multi-Pinhole Collimator for I-123 DaTscan Imaging on Dual-Headed SPECT Systems in Combination with a Fan-Beam Collimator.

Authors:  Michael A King; Joyeeta M Mukherjee; Arda Könik; I George Zubal; Joyoni Dey; Robert Licho
Journal:  IEEE Trans Nucl Sci       Date:  2016-02-03       Impact factor: 1.679

4.  Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications.

Authors:  Jason D Bowen; Qiu Huang; Justin R Ellin; Tzu-Cheng Lee; Uttam Shrestha; Grant T Gullberg; Youngho Seo
Journal:  Phys Med Biol       Date:  2013-09-24       Impact factor: 3.609

5.  Development and Evaluation of Image Reconstruction Algorithms for a Novel Desktop SPECT System.

Authors:  Navid Zeraatkar; Arman Rahmim; Saeed Sarkar; Mohammad Reza Ay
Journal:  Asia Ocean J Nucl Med Biol       Date:  2017
  5 in total

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