Literature DB >> 16177777

Pharmaceuticals: a new grammar for drug discovery.

Mark C Fishman, Jeffery A Porter.   

Abstract

Mesh：

Year:  2005        PMID： 16177777     DOI： 10.1038/437491a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  44 in total

Review 1.  Pharmacology of intracellular signalling pathways.

Authors:  Stefan R Nahorski
Journal:  Br J Pharmacol       Date:  2006-01       Impact factor: 8.739

Review 2.  Decompartmentalizing target validation-thinking outside the pipeline boxes.

Authors:  Rob Hooft van Huijsduijnen; Christian Rommel
Journal:  J Mol Med (Berl)       Date:  2006-08-05       Impact factor: 4.599

3.  Unraveling the molecular targets pertinent to junction restructuring events during spermatogenesis using the Adjudin-induced germ cell depletion model.

Authors:  Weiliang Xia; Dolores D Mruk; Will M Lee; C Yan Cheng
Journal:  J Endocrinol       Date:  2007-03       Impact factor: 4.286

Review 4.  Ligand discovery and virtual screening using the program LIDAEUS.

Authors:  P Taylor; E Blackburn; Y G Sheng; S Harding; K-Y Hsin; D Kan; S Shave; M D Walkinshaw
Journal:  Br J Pharmacol       Date:  2007-11-26       Impact factor: 8.739

Review 5.  A network view of disease and compound screening.

Authors:  Eric E Schadt; Stephen H Friend; David A Shaywitz
Journal:  Nat Rev Drug Discov       Date:  2009-04       Impact factor: 84.694

6.  Human genetics as a foundation for innovative drug development.

Authors:  Alexander Kamb; Sean Harper; Kari Stefansson
Journal:  Nat Biotechnol       Date:  2013-11       Impact factor: 54.908

Review 7.  Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds.

Authors:  Yan Feng; Timothy J Mitchison; Andreas Bender; Daniel W Young; John A Tallarico
Journal:  Nat Rev Drug Discov       Date:  2009-07       Impact factor: 84.694

Review 8.  European regulation on orphan medicinal products: 10 years of experience and future perspectives.

Authors:  Kerstin Westermark; Birthe Byskov Holm; Mirjam Söderholm; Jordi Llinares-Garcia; Frida Rivière; Stiina Aarum; Florence Butlen-Ducuing; Stelios Tsigkos; Agnieszka Wilk-Kachlicka; Cinzia N'Diamoi; János Borvendég; David Lyons; Bruno Sepodes; Brigitte Bloechl-Daum; André Lhoir; Mariana Todorova; Ioannis Kkolos; Kateřina Kubáčková; Heidrun Bosch-Traberg; Vallo Tillmann; Veijo Saano; Emmanuel Héron; Rembert Elbers; Miranda Siouti; Judit Eggenhofer; Patrick Salmon; Maurizio Clementi; Dainis Krieviņš; Aušra Matulevičiene; Henri Metz; Albert Cilia Vincenti; Albertha Voordouw; Bożenna Dembowska-Bagińska; Ana Corrêa Nunes; Flavia Mirela Saleh; Tatiana Foltánová; Martin Možina; Josep Torrent i Farnell; Björn Beerman; Segundo Mariz; Marie Pauline Evers; Lesley Greene; Sigurdur Thorsteinsson; Lars Gramstad; Maria Mavris; Fabrizia Bignami; Annie Lorence; Chantal Belorgey
Journal:  Nat Rev Drug Discov       Date:  2011-05       Impact factor: 84.694

Review 9.  Fibrodysplasia ossificans progressiva (FOP): A disorder of osteochondrogenesis.

Authors:  Frederick S Kaplan; Mona Al Mukaddam; Alexandra Stanley; O Will Towler; Eileen M Shore
Journal:  Bone       Date:  2020-07-27       Impact factor: 4.398

10.  The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression.

Authors:  Nan Cai; Wei Zhou; Lan-Lan Ye; Jun Chen; Qiu-Ni Liang; Gang Chang; Jia-Jie Chen
Journal:  Am J Transl Res       Date:  2017-08-15       Impact factor: 4.060
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