Literature DB >> 16145708

Effective removal of albumin from serum.

David A Colantonio1, Christy Dunkinson, Diane E Bovenkamp, Jennifer E Van Eyk.   

Abstract

The protein constituents of serum can range from grams to picograms per liter, making it technically difficult to achieve in-depth proteomic analysis. Removal of highly abundant proteins, such as albumin, coupled to powerful protein separation methods is required for increased sample load, thus facilitating detection and identification of low-abundant proteins. We report here a chemical-based extraction method for the effective and specific removal of albumin from serum.

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Year:  2005        PMID： 16145708     DOI： 10.1002/pmic.200401235

Source DB:  PubMed          Journal:  Proteomics        ISSN： 1615-9853            Impact factor:   3.984


  22 in total

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