| Literature DB >> 20526430 |
Stephen B Mason1, Xianyin Lai, Robert L Bacallao, Bonnie L Blazer-Yost, Vincent H Gattone, Kevin C Wang, Frank A Witzmann.
Abstract
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is characterized by the development of numerous fluid-filled cysts in the kidneys of patients. We recently published our description of the proteome of renal cyst fluid in ADPKD. As a follow-up experiment, we hypothesized that the protein-bound subfraction consists of molecules of mechanistic or diagnostic interest in ADPKD. Using a manual biomarker enrichment kit, we have identified 44 distinct proteins in human cyst fluid.Entities:
Year: 2009 PMID: 20526430 PMCID: PMC2880522 DOI: 10.1002/prca.200800163
Source DB: PubMed Journal: Proteomics Clin Appl ISSN: 1862-8346 Impact factor: 3.494